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Michel, Maximilian; Green, Charity L.; Lyons, Lisa C. – Learning & Memory, 2011
We investigated the involvement of PKA and PKC signaling in a negatively reinforced operant learning paradigm in "Aplysia", learning that food is inedible (LFI). In vivo injection of PKA or PKC inhibitors blocked long-term LFI memory formation. Moreover, a persistent phase of PKA activity, although not PKC activity, was necessary for long-term…
Descriptors: Long Term Memory, Food, Learning, Models