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Rubenstein, Eric; Young, Jessica C.; Croen, Lisa A.; DiGuiseppi, Carolyn; Dowling, Nicole F.; Lee, Li-Ching; Schieve, Laura; Wiggins, Lisa D.; Daniels, Julie – Journal of Autism and Developmental Disorders, 2019
Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism…
Descriptors: Mothers, Narcotics, Autism, Pervasive Developmental Disorders
Yau, Vincent M.; Lutsky, Marta; Yoshida, Cathleen K.; Lasley, Bill; Kharrazi, Martin; Windham, Gayle; Gee, Nancy; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2015
Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000-2001 were identified: ASD (n = 78), developmental delay…
Descriptors: Metabolism, Autism, Pervasive Developmental Disorders, Pregnancy
Measures of Cortical Grey Matter Structure and Development in Children with Autism Spectrum Disorder
Mak-Fan, Kathleen M.; Taylor, Margot J.; Roberts, Wendy; Lerch, Jason P. – Journal of Autism and Developmental Disorders, 2012
The current study examined group differences in cortical volume, surface area, and thickness with age, in a group of typically developing children and a group of children with ASD aged 6-15 years. Results showed evidence of age by group interactions, suggesting atypicalities in the relation between these measures and age in the ASD group.…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Brain
Pfeifer, Jennifer H.; Merchant, Junaid S.; Colich, Natalie L.; Hernandez, Leanna M.; Rudie, Jeff D.; Dapretto, Mirella – Journal of Autism and Developmental Disorders, 2013
This fMRI study investigated neural responses while making appraisals of self and other, across the social and academic domains, in children and adolescents with and without autism spectrum disorders (ASD). Compared to neurotypical youth, those with ASD exhibited hypoactivation of ventromedial prefrontal cortex during self-appraisals. Responses in…
Descriptors: Brain, Autism, Neurological Organization, Behavior
McPartland, James C.; Pelphrey, Kevin A. – Journal of Autism and Developmental Disorders, 2012
Social disability represents a unifying feature in the diverse group of individuals with autism spectrum disorder (ASD). Social neuroscience is the study of brain mechanisms supporting interpersonal interaction. In this paper, we review brain imaging studies of the social brain and highlight practical applications of these scientific insights.…
Descriptors: Autism, Neurology, Brain, Antisocial Behavior
Rommelse, Nanda N. J.; Peters, Cindy T. R.; Oosterling, Iris J.; Visser, Janne C.; Bons, Danielle; van Steijn, Daphne J.; Draaisma, Jos; van der Gaag, Rutger-Jan; Buitelaar, Jan. K. – Journal of Autism and Developmental Disorders, 2011
The aims of the current study were to examine whether early growth abnormalities are (a) comparable in autism spectrum disorders (ASD) and other childhood psychiatric disorders, and (b) specific to the brain or generalized to the whole body. Head circumference, height, and weight were measured during the first 19 months of life in 129 children…
Descriptors: Autism, Children, Pervasive Developmental Disorders, Human Body