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Direct linkSzucs, Denes; Soltesz, Fruzsina; Bryce, Donna; Whitebread, David – Journal of Cognitive Neuroscience, 2009
The ability to select an appropriate motor response by resolving competition among alternative responses plays a major role in cognitive performance. fMRI studies suggest that the development of this skill is related to the maturation of the frontal cortex that underlies the improvement of motor inhibition abilities. However, fMRI cannot…
Descriptors: Inhibition, Competition, Child Development, Motor Reactions
Verbitsky, Miguel; Yonan, Amanda L.; Malleret, Gael; Kandel, Eric R.; Gilliam, T. Conrad; Pavlidis, Paul – Learning & Memory, 2004
We have carried out a global survey of age-related changes in mRNA levels in the 57BL/6NIA mouse hippocampus and found a difference in the hippocampal gene expression profile between 2-month-old young mice and 15-month-old middle-aged mice correlated with an age-related cognitive deficit in hippocampal-based explicit memory formation. Middle-aged…
Descriptors: Profiles, Animals, Memory, Brain Hemisphere Functions
