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Direct linkDeirdre M. McCarthy; Thomas J. Spencer; Pradeep G. Bhide – Journal of Attention Disorders, 2024
Objective: We offer an overview of ADHD research using mouse models of nicotine exposure. Method: Nicotine exposure of C57BL/6 or Swiss Webster mice occurred during prenatal period only or during the prenatal and the preweaning periods. Behavioral, neuroanatomical and neurotransmitter assays were used to investigate neurobiological mechanisms of…
Descriptors: Models, Attention Deficit Hyperactivity Disorder, Smoking, Animals
Muehlmann, A. M.; Kies, S. D.; Turner, C. A.; Wolfman, S.; Lewis, M. H.; Devine, D. P. – Journal of Intellectual Disability Research, 2012
Background: Self-injurious behaviour (SIB) is prevalent in neurodevelopmental disorders, but its expression is highly variable within, and between diagnostic categories. This raises questions about the factors that contribute to aetiology and expression of SIB. Expression of SIB is generally described in relation to social reinforcement. However,…
Descriptors: Animals, Injuries, Neurology, Rating Scales
Butler, Robert W.; Sahler, Olle Jane Z.; Askins, Martha A.; Alderfer, Melissa A.; Katz, Ernest R.; Phipps, Sean; Noll, Robert B. – Developmental Disabilities Research Reviews, 2008
A very brief historical review on the identification of neurocognitive deficits in patients treated for a pediatric malignancy that involved CNS disease, treatment, or a combination is provided. This review is particularly directed toward providing a foundation upon which the introduction of specific brain injury rehabilitation efforts and…
Descriptors: History, Stimulants, Injuries, Cancer
Kolb, Bryan; Pellis, Sergio; Robinson, Terry E. – Brain and Cognition, 2004
We compare the effects of psychoactive drugs such as morphine and amphetamine on the synaptic organization of neurons in the orbital frontal (OFC) and medial frontal (mPFC) regions in the rat. Both regions are altered chronically by exposure to intermittent doses of either drug but the effects are area-dependent. For example, whereas morphine…
Descriptors: Brain, Animals, Social Behavior, Drug Use
