Over 70 years ago Dr. Karel Bobath and his wife Bertha Bobath began to craft the therapeutic intervention now known as neurodevelopmental treatment (NDT). This edition of Reviews, Tools, and Resources will highlight a historical review of research studies that have been completed, current websites, books, and blogs focusing on NDT.

Early caregiving experiences play a central role in shaping emotional development, stress physiology, and refinement of limbic circuitry. Converging evidence across species delineates a sensitive period of heightened neuroplasticity when frontoamygdala circuitry is especially amenable to caregiver inputs early in life. During this period, parental…

How does the brain's response to speech change over the first months of life? Although behavioral findings indicate that neonates' listening biases are sharpened over the first months of life, with a species-specific preference for speech emerging by 3 months, the neural substrates underlying this developmental change are unknown. We…

Adolescence is a period of profound change, which holds substantial developmental milestones, but also unique challenges to the individual. In this opinion paper, we highlight the potential of combining two recently developed behavioural and neural training techniques (cognitive bias modification and functional magnetic neuroimaging-based…

Case studies of extremely gifted individuals often reveal unique patterns of intellectual precocity and associated abnormalities in development and behavior. This article begins with a review of current neurophysiological and neuroanatomical findings related to the gifted population. The bulk of scientific inquiries provide evidence of unique…

Neuronal plasticity allows the central nervous system to learn skills and remember information, to reorganize neuronal networks in response to environmental stimulation, and to recover from brain and spinal cord injuries. Neuronal plasticity is enhanced in the developing brain and it is usually adaptive and beneficial but can also be maladaptive…

Early adversity, for example poor caregiving, can have profound effects on emotional development. Orphanage rearing, even in the best circumstances, lies outside of the bounds of a species-typical caregiving environment. The long-term effects of this early adversity on the neurobiological development associated with socio-emotional behaviors are…

Although research has focused primarily on the wide range of variability in the cognitive phenotype between individuals with velo-cardio-facial syndrome (VCFS), we know relatively little about the extent to which within-individual expressions of the cognitive phenotype remain stable throughout development. General cognitive functioning in the low…

The second in a series of three articles concerning children's brain development focuses on the organization of the brain. Aspects of the brain's vertical, neocortex, and temporal organization are discussed and references for further reading are provided. (CJ)

Notes that scientists understand in greater detail the various anatomical and neurological changes that allow children to develop motor and sensory abilities. Explores how the research findings are calling into question the notion of prescribed developmental milestones. (HTH)

Recurring seizures in infants and children are often associated with cognitive deficits, but the reason for the learning difficulties is unclear. Recent studies in several animal models suggest that seizures themselves may contribute in important ways to these deficits. Other studies in animals have shown that recurring seizures result in…

A wide variety of tests are available to assess the central nervous system (CNS) function of the toddler and preschool-aged child. These tests vary as to function; qualities and abilities tapped; facility with which they can be learned, administered, and scored; availability of test materials and manuals or training videos; and strength of…

Research shows that children of about 10 years can remember photographs of faces upside down almost as well as those shown upright and are easily fooled by simple disguises. This ability to encode orientation-specific configurations of a face may reflect maturational changes in the right cerebral hemisphere. (MLH)

The article discusses neuropsychological and treatment aspects of brain behavior disorders in children from the standpoint of terms such as minimal brain dysfunction, learning disabilities, hyperactivity, and hyperkinetic syndrome. (Author/DLS)

This book describes a neuro-developmental approach to learning difficulty assessment and remediation through assessment of a student's reception of information through the sensory channels, processing of sensory information in the brain, and repertoire of responses for expression. Chapter 1, "Reflexes: Their Impact on Success or Failure in…