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Direct linkSingh, Anoushka; Miller, Ryan C.; Archuleta, Stephen R.; Kugel, Jennifer F. – Biochemistry and Molecular Biology Education, 2023
Transcription is the critical first step in expressing a gene, during which an RNA polymerase (RNAP) synthesizes an RNA copy of one strand of the DNA that encodes a gene. Here we describe a laboratory experiment that uses a single assay to probe two important steps in transcription: (1) RNAP binding to DNA, and (2) the transcriptional activity of…
Descriptors: Molecular Biology, Science Instruction, Genetics, Teaching Methods
Andrew Phillips; Anusha Srinivas; Ilina Prentoska; Margaret O'Dea; Matthew Kustrup; Sarah Hurley; Savannah Bruno; Vy Nguyen; Pin-Kuang Lai – Biochemistry and Molecular Biology Education, 2024
Teaching chemistry and biology students about biologics design remains challenging despite its increasing importance in pharmaceutical development. Monoclonal antibodies, commonly called mAbs, are the most popular biologics. They have been developed into drugs to treat various diseases in the past decades. Multiple challenges exist for designing…
Descriptors: Teaching Methods, Biochemistry, Science Instruction, Computer Software
Suárez Casanova, Víctor Manuel; Shumskaya, Maria – Biochemistry and Molecular Biology Education, 2021
DNA structure has been leveraged in a variety of facets that allow scientists to perform a range of assays, including ones for identification of species, establishing evolutionary relationships between taxa, or even identifying individuals. Here, we present a DNA barcoding method as practical, hands-on approach that connects several experimental…
Descriptors: Genetics, Biochemistry, Science Instruction, Molecular Biology
Khorsand, Babak; Khammari, Anahita; Shirvanizadeh, Niloofar; Zahiri, Javad; Arab, Seyed Shahriar – Biochemistry and Molecular Biology Education, 2019
Today smartphones are inseparable parts of modern life and are capable of performing many desktop computers' tasks such as scientific analysis with greater convenience. Here, we present OligoCOOL, which is an Android application for analyzing nucleic sequences. This application enables users to perform several common biomedical analyses for a…
Descriptors: Teaching Methods, Science Instruction, Biochemistry, Telecommunications
Yang, Xiaohan; Zhou, Xuehong; Yi, Xia; Zhang, Weifang; Yang, Yang; Ni, Juhua – Biochemistry and Molecular Biology Education, 2021
Biochemistry is an important curriculum for all medical students but has long been considered obscure and of very little or indirect relevance to medical or clinical practice, which markedly diminishes the enthusiasm and motivation of medical students in learning. Biochemistry teachers always face a tremendous challenge to deliver an attractive…
Descriptors: Science Instruction, Active Learning, Teaching Methods, Lecture Method
Download full textCharlotte A. Dodson; Stephen E. Flower; Mark Thomas – Journal of Chemical Education, 2023
Industrial drug discovery teams encompass scientists from multiple specialties and require participants to communicate effectively across disciplinary boundaries. In this paper, we present an undergraduate or graduate classroom simulation of this environment. Over a series of five workshops, student teams of mixed scientific backgrounds perform…
Descriptors: Drug Therapy, Pharmacy, Teamwork, Interdisciplinary Approach
Sherrer, Shanen M. – Biochemistry and Molecular Biology Education, 2020
Virtual laboratory activities are flexible approaches to engage undergraduate students in scientific practices during the COVID-19 pandemic. By utilizing online simulations, students can conduct virtual experiments on important biochemical reactions that occur during photosynthesis. The learning module described here provides students with this…
Descriptors: Computer Simulation, Undergraduate Students, COVID-19, Pandemics
Denis, Colette; Lasfargues, Charline; Buffin-Meyer, Bénédicte – Biochemistry and Molecular Biology Education, 2021
The practical work described here is designed for third-year bachelor students in Life Sciences attending a kidney physiology course. It illustrates how urinary biochemistry can be used for a medical diagnosis. Students have to measure glucose, proteins, and creatinine concentrations in three simulated urine samples. First, they independently…
Descriptors: Biochemistry, Science Instruction, Diseases, Teaching Methods
Large, Delaney N.; Van Doorn, Nathaniel A.; Timmons, Shannon C. – Biochemistry and Molecular Biology Education, 2023
Laboratory courses should cultivate enthusiasm for research and an appreciation for real-world scientific challenges to retain undergraduate students and encourage them to pursue STEM-related careers. Course-based undergraduate research experiences (CURE) have emerged as an inclusive pedagogical model that facilitates laboratory skill development,…
Descriptors: Cancer, Laboratory Experiments, Undergraduate Students, STEM Careers
Sarisky, Catherine A.; Johann, Timothy W. – Journal of Chemical Education, 2018
A semester-long hypothesis-driven laboratory project for second-semester biochemistry has been developed. Working independently, students propose a hypothesis about the role of one amino acid residue in the active site of 5,10-methenyltetrahydrofolate synthetase (MTHFS). They then test this hypothesis by site-directed mutagenesis of a plasmid…
Descriptors: Biochemistry, Science Instruction, Laboratory Experiments, Course Descriptions
Mello, P. S.; Natale, C. C.; Trivelato, S. L. F.; Marzin-Janvier, P.; Vieira, L. Q.; Manzoni-de-Almeida, D. – Biochemistry and Molecular Biology Education, 2019
This article examines student engagement in an inquiry-based learning activity, planned to provide students with elements in the social, epistemic, and conceptual dimensions related to the scientific practice in immunology. The activity was applied to 39 groups of students enrolled in immunology or biochemistry courses in a public university in…
Descriptors: Science Instruction, Inquiry, Learning Activities, Epidemiology
Cicuto, Camila; Pazinato, Maurícius; Torres, Bayardo – Biochemistry and Molecular Biology Education, 2019
Scientific articles have been explored as a didactic resource in the teaching of Biochemistry, as well as in other areas of science. This teaching strategy contributes to the learning and understanding of specific concepts, and development of the skills, necessary for the research training of students. The present study investigated the use of…
Descriptors: Science Instruction, Teaching Methods, Metabolism, Scientific Concepts
Erin C. Yang; Robby Divine; Christine S. Kang; Sidney Chan; Elijah Arenas; Zoe Subol; Peter Tinker; Hayden Manninen; Alicia Feichtenbiner; Talal Mustafa; Julia Hallowell; Isiac Orr; Hugh Haddox; Brian Koepnick; Jacob O'Connor; Ian C. Haydon; Karla-Luise Herpoldt; Kandise Van Wormer; Celine Abell; David Baker; Alena Khmelinskaia; Neil P. King – Journal of Chemical Education, 2022
Undergraduate research experiences can improve student success in graduate education and STEM careers. During the COVID-19 pandemic, undergraduate researchers at our institution and many others lost their work-study research positions due to interruption of in-person research activities. This imposed a financial burden on the students and…
Descriptors: Undergraduate Students, Teaching Methods, COVID-19, Pandemics
Taylor, Ann T. S. – Biochemistry and Molecular Biology Education, 2020
One of the goals for requiring all college students to take science courses is to develop critical thinking about scientific issues they will encounter as citizens, consumers, and patients. This article integrates skill development activities targeting civic scientific literacy skills in a nonscience majors (liberal arts) biochemistry course, but…
Descriptors: Scientific Literacy, Biochemistry, Science Instruction, Nonmajors
Jeffery, Kathleen A. – ProQuest LLC, 2019
Recent calls in education have emphasized the critical need for curricula in the sciences to support student development of the general and disciplinary-specific practices that are relevant to modern scientific research and careers, as well as foundational scientific knowledge that reflects recent advances. In this regard, the life sciences,…
Descriptors: Biochemistry, Science Education, Science Instruction, Biological Sciences
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