Regional Educational Laboratory Southwest conducted this literature review to identify malleable factors that can be measured in K-12 settings and that predict students' postsecondary science, technology, engineering, and math (STEM) success (defined as enrolling in, persisting in, and completing a postsecondary STEM major or degree), particularly for Hispanic students. The review found that courses taken in high school and interest or confidence in STEM were strong predictors of postsecondary STEM success for students of all racial/ethnic subgroups. Yet racial/ethnic minority students were less likely than White students to take the highest level math and science courses, and despite similar levels of STEM interest, racial/ethnic minority students were less likely to achieve postsecondary STEM success. Other indicators of postsecondary STEM success included high school grade point average, class rank, math and science achievement, and SAT or ACT scores. Grades in math and science courses were found to be less predictive of postsecondary STEM success for racial/ethnic minority students than for White students. [For the full report, see ED565641.]