Introduction: The aim of this study was to adapt the Health of the Nation Outcome Scales for people with Learning Disabilities into French (F-HoNOS-LD) and to examine its validity and reliability. Method: Sixty-six adults with intellectual disabilities (ID) admitted to a psychiatric hospital took part in the study. Clinicians used the F-HoNOS-LD…

Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…

Background: As both epilepsy and challenging behaviour are highly prevalent in adults with intellectual disability (ID) it is important to explore any potential relationships between the two to inform patient care. The aim of the present study was to investigate the relationship between epilepsy factors and challenging behaviour in adults with ID.…

Introduction: The purpose of this study was to gain additional insight on patterns of behavior of three individuals dually diagnosed with intellectual disability (ID) and bipolar disorder as they cycled between elevated and depressed mood states. Methods: Data were collected from weekly, one-hour observations across a period of several months. The…

Nicotinic acetylcholine receptors (nAChRs), particularly the a7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight…

Progress in clinical research and in empirically supported interventions in the area of psychopathology in intellectual disabilities (ID) depends on high-quality assessment instruments. To this end, psychometric properties of four instruments were examined: the "Aberrant Behavior Checklist" (ABC), the "Assessment of Dual…

Background: Many people with intellectual disabilities display high levels of anger, and cognitive-behavioural anger management interventions are used routinely. However, for these methods to be used optimally, a better understanding is needed of different forms of anger assessment. The aim of this study was to investigate the relationship of a…

Background: The triad of impairments characteristic of autistic spectrum disorders and severe challenging behaviours are reasonably common among adults with intellectual disabilities. The aim was to investigate whether they had an impact on lifestyle among such adults living in staff-supported community housing. Methods: Data were collected on the…

Nurses applied standard behavioral criteria for major depression to evaluate 89 institutionalized adults with severe or profound intellectual disability. Results suggested that several additional behaviors listed on the Aberrant Behavior Checklist and the Developmental Behavior Checklist may be associated with this disorder in this population.…

A study compared the Aberrant Behavior Checklist (ABC) and the Behavior Problems Inventory (BPI) for assessing the maladaptive behavior of 226 adults, mostly with severe or profound mental retardation. Individuals with elevated BPI scores generally had higher ABC scores, however, the extent of covariation differed across subscales. (Contains…

For comparison with ratings previously obtained in New Zealand, the study analyzed subscales of the Aberrant Behavior Checklist using 531 moderately and severely retarded subjects from a residential institution in the United States. Sex failed to influence subscale scores, whereas age, country, and severity of retardation significantly affected…