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Direct linkAlison Fong; Robin Friedlander; Anamaria Richardson; Katie Allen; Qian Zhang – International Journal of Developmental Disabilities, 2024
Objective: This study aims to delineate the characteristics of severe self-injurious behaviors (SIB) in a cohort of children with autism and unspecified intellectual developmental disorder (UIDD) (intellectual disability) and examine potential risk factors for developing SIB. Methods: A retrospective chart review studied characteristics of severe…
Descriptors: Self Destructive Behavior, Children, Autism Spectrum Disorders, Developmental Disabilities
Lewis, Alan S.; van Schalkwyk, Gerrit Ian; Lopez, Mayra Ortiz; Volkmar, Fred R.; Picciotto, Marina R.; Sukhodolsky, Denis G. – Journal of Autism and Developmental Disorders, 2018
Nicotinic acetylcholine receptors (nAChRs), particularly the a7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight…
Descriptors: Aggression, Adults, Stimulants, Pervasive Developmental Disorders
