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Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Simonoff, Emily; Taylor, Eric; Baird, Gillian; Bernard, Sarah; Chadwick, Oliver; Liang, Holan; Whitwell, Susannah; Riemer, Kirsten; Sharma, Kishan; Sharma, Santvana Pandey; Wood, Nicky; Kelly, Joanna; Golaszewski, Ania; Kennedy, Juliet; Rodney, Lydia; West, Nicole; Walwyn, Rebecca; Jichi, Fatima – Journal of Child Psychology and Psychiatry, 2013
Background: Attention deficit hyperactivity disorder is increased in children with intellectual disability. Previous research has suggested stimulants are less effective than in typically developing children but no studies have titrated medication for individual optimal dosing or tested the effects for longer than 4 weeks. Method: One hundred and…
Descriptors: Attention Deficit Hyperactivity Disorder, Children, Mental Retardation, Drug Therapy
Aman, Michael G.; Hollway, Jill A.; Leone, Sarah; Masty, Jessica; Lindsay, Ronald; Nash, Patricia; Arnold, L. Eugene – Research in Developmental Disabilities: A Multidisciplinary Journal, 2009
This study was designed to explore the placebo-controlled effects of risperidone on cognitive-motor processes, dyskinetic movements, and behavior in children receiving maintenance risperidone therapy. Sixteen children aged 4-14 years with disruptive behavior were randomly assigned to drug order in a crossover study of risperidone and placebo for 2…
Descriptors: Metabolism, Behavior Problems, Reaction Time, Hyperactivity