NotesFAQContact Us
Collection
Advanced
Search Tips
Showing all 7 results Save | Export
The Network Structure of Irritability and Aggression in Individuals with Autism Spectrum Disorder
Peer reviewed Peer reviewed
Direct linkDirect link
Hirota, Tomoya; Deserno, Marie; McElroy, Eoin – Journal of Autism and Developmental Disorders, 2020
Irritability and aggression (IA) are highly prevalent in individuals with autism spectrum disorder (ASD). Although clinical correlates of IA in this population have been previously examined, findings from existing studies capturing symptoms as a set of latent variables do not fully explain meaningful associations between the symptoms themselves.…
Descriptors: Aggression, Antisocial Behavior, Autism, Pervasive Developmental Disorders
Measuring Repetitive Behaviors as a Treatment Endpoint in Youth with Autism Spectrum Disorder
Peer reviewed Peer reviewed
Direct linkDirect link
Scahill, Lawrence; Aman, Michael G.; Lecavalier, Luc; Halladay, Alycia K.; Bishop, Somer L.; Bodfish, James W.; Grondhuis, Sabrina; Jones, Nancy; Horrigan, Joseph P.; Cook, Edwin H.; Handen, Benjamin L.; King, Bryan H.; Pearson, Deborah A.; McCracken, James T.; Sullivan, Katherine Anne; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2015
Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized…
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Problems, Repetition
Brief Report: Pilot Single-Blind Placebo Lead-in Study of Acamprosate in Youth with Autistic Disorder
Peer reviewed Peer reviewed
Direct linkDirect link
Erickson, Craig A.; Wink, Logan K.; Early, Maureen C.; Stiegelmeyer, Elizabeth; Mathieu-Frasier, Lauren; Patrick, Vanessa; McDougle, Christopher J. – Journal of Autism and Developmental Disorders, 2014
Rationale: An excitatory/inhibitory (E:I) imbalance marked by enhanced glutamate and deficient gamma-aminobutyric acid (GABA) neurotransmission may contribute to the pathophysiology of autism spectrum disorders (ASD). Objectives: We report on the first single-blind placebo lead-in trial of acamprosate, a drug with putative mechanisms restoring E:I…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Metabolism
Telephone Administration of the Aberrant Behavior Checklist: A Pilot Study of Feasibility in Children with Intellectual Disability and Autism
Peer reviewed Peer reviewed
Direct linkDirect link
Siegel, Matthew; Milligan, Briana; Stein, Hannah; Teer, Olivia; Smith, Kahsi A. – Journal of Intellectual Disabilities, 2013
To advance clinical care and research in children with intellectual disability and autism there is a growing need for efficient means to measure behavioral severity and response to treatment. The objective of this study was to assess the feasibility of telephone administration of the Aberrant Behavior Checklist-Irritability Subscale (ABC-I). The…
Descriptors: Telephone Surveys, Antisocial Behavior, Check Lists, Feasibility Studies
Assessing Anger in People with Intellectual Disability
Peer reviewed Peer reviewed
Direct linkDirect link
Rose, John L.; Gerson, Danielle F. – Journal of Intellectual & Developmental Disability, 2009
Background: There is a growing interest in the use of cognitive approaches for the treatment of psychological difficulties with people who have intellectual disability. The aim of the present study was to investigate the properties of an anger inventory, the relationship between self-reported and staff-reported levels of anger, and the…
Descriptors: Intervention, Mental Retardation, Psychological Patterns, Correlation
A Comparison of Repetitive Behaviors in Aspergers Disorder and High Functioning Autism
Peer reviewed Peer reviewed
Direct linkDirect link
Cuccaro, Michael L.; Nations, Laura; Brinkley, Jason; Abramson, Ruth K.; Wright, Harry H.; Hall, Alicia; Gilbert, John; Pericak-Vance, Margaret A. – Child Psychiatry and Human Development, 2007
In this study we compared 33 IQ and age matched pairs of individuals with Aspergers Disorder (ASP) and high functioning autism (HFA) on measures of repetitive behavior. On the Repetitive Behavior Scale-Revised (RBS-R), the ASP and HFA groups showed no differences in RBS-R Intensity score (severity) score or Frequency score (number of problems…
Descriptors: Severity (of Disability), Autism, Antisocial Behavior, Asperger Syndrome
Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial
Peer reviewed Peer reviewed
Direct linkDirect link
Pandina, Gahan J.; Bossie, Cynthia A.; Youssef, Eriene; Zhu, Young; Dunbar, Fiona – Journal of Autism and Developmental Disorders, 2007
Subgroup analysis of children (5-12 years) with autism enrolled in an 8-week, double-blind, placebo-controlled trial of risperidone for pervasive developmental disorders. The primary efficacy measure was the Aberrant Behavior Checklist-Irritability (ABC-I) subscale. Data were available for 55 children given risperidone (n = 27) or placebo (n =…
Descriptors: Autism, Drug Therapy, Children, Behavior Modification