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Grigorenko, Elena L.; Dozier, Mary – Child Development, 2013
The debate about the relevance of human genetics knowledge to everyday life has been marked by fluctuations of interest and enthusiasm. The negative impact of eugenics on the public consciousness suppressed dialogue between geneticists and the public for most of the second half of the 20th century (Ridley, 1999). For the most part, nongeneticists…
Descriptors: Genetics, Public Health, Genetic Disorders, Scientific Research
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Connolly, John J.; Glessner, Joseph T.; Hakonarson, Hakon – Child Development, 2013
Efforts to understand the causes of autism spectrum disorders (ASDs) have been hampered by genetic complexity and heterogeneity among individuals. One strategy for reducing complexity is to target endophenotypes, simpler biologically based measures that may involve fewer genes and constitute a more homogenous sample. A genome-wide association…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Genetic Disorders
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Landa, Rebecca J.; Gross, Alden L.; Stuart, Elizabeth A.; Faherty, Ashley – Child Development, 2013
Retrospective studies indicate 2 major classes of autism spectrum disorder (ASD) onset: early and later, after a period of relatively healthy development. This prospective, longitudinal study examined social, language, and motor trajectories in 235 children with and without a sibling with autism, ages 6-36 months. Children were grouped as: ASD…
Descriptors: Pervasive Developmental Disorders, Autism, Comparative Analysis, Longitudinal Studies