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Poor Fine-Motor and Visuospatial Skills Predict Persistence of Pediatric-Onset Obsessive-Compulsive Disorder into Adulthood
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Bloch, Michael H.; Sukhodolsky, Denis G.; Dombrowski, Philip A.; Panza, Kaitlyn E.; Craiglow, Brittany G.; Landeros-Weisenberger, Angeli; Leckman, James F.; Peterson, Bradley S.; Schultz, Robert T. – Journal of Child Psychology and Psychiatry, 2011
Background: Half of pediatric-onset OCD cases remit by adulthood. Studies have demonstrated that initial response to pharmacotherapy, age of onset, prominent hoarding symptoms, and the presence of comorbid tic disorders are associated with long-term outcome. Our goal was to examine the association between childhood performance on…
Descriptors: Anxiety Disorders, Intelligence, Persistence, Children
An Extra X or Y Chromosome: Contrasting the Cognitive and Motor Phenotypes in Childhood in Boys with 47,XYY Syndrome or 47,XXY Klinefelter Syndrome
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Ross, Judith L.; Zeger, Martha P. D.; Kushner, Harvey; Zinn, Andrew R.; Roeltgen, David P. – Developmental Disabilities Research Reviews, 2009
Objective: The goal of this study was to contrast the cognitive phenotypes in boys with 47,XYY (XYY) karyotype and boys with 47,XXY karyotype [Klinefelter syndrome, (KS)], who share an extra copy of the X-Y pseudoautosomal region but differ in their dosage of strictly sex-linked genes. Methods: Neuropsychological evaluation of general cognitive…
Descriptors: Genetic Disorders, Males, Sex, Genetics