Due to the increase of re-entry women in college, investigation of interest inventories for this particular population has become essential. Four studies involving 239 mature women are reported which examine the effect of changing instructions on expressed interests; the expressed satisfaction of mature women with KOIS results; the extent of profile differentiation; and the usefulness of male-normed scales with female clients. Conclusions are that the KOIS can be effectively used with re-entry women and that the profiles do reflect individual diversity; re-entry women consider KOIS results reasonable and the KOIS responses are not easily manipulated. Most women score higher on the female-normed scales than the corresponding same-normed male-normed scales; cross sex scales should be examined by women to expand alternatives considered. (Author)