The Philippines implemented its educational reform commonly known as K to 12 Program in 2013 for Filipino learners' holistic development and global competitiveness. One indicator of the reform's effectiveness is the country's performance in international large-scale assessments like the Trends in International Mathematics and Science Study (TIMSS), if it participates again in 2019. To gauge readiness and inform decisions on its participation, this study examines the alignment of TIMSS 2015 Assessment Framework vis-à-vis the 2016 Philippine's K to 12 Curriculum in Mathematics and Science. Through curriculum mapping of experts on the competencies in the two documents, the study reveals that K to 12 Mathematics Grade 4 is more aligned with TIMSS 2015 Assessment Framework than that of Math Grade 8, Science Grade 4, and Science Grade 8. The study recommends continuous curriculum improvement of the Philippine's K to 12 Curriculum and implementation of relevant intervention programs and support system from different education stakeholders, including country-based publishing and testing companies to address gaps on competencies found for the country to meet international benchmarks.