While overall graduation rates are improving, persistent disparities in graduation rates among groups of students remain, and must be addressed. High school reform is a viable approach to addressing these disparities. Early College High Schools, Small Schools of Choice, and Career Academies are all secondary school reform models that have been rigorously studied and shown to improve student outcomes in many areas, including math and reading achievement, high school graduation, postsecondary enrollment, and earnings later in life. This report seeks to assist practitioners and policymakers in education in making systematic, evidence-based decisions. The authors: (1) Reviewed 13 evaluations of comprehensive reform efforts, identified the features of the models evaluated, and categorized them to create a high school reform framework that can be generally applied. The authors hope that school and district leaders can compare their current efforts with the framework to identify how they might refine or augment those efforts; and (2) Compiled information on prevalent features of reform models that have proven promising for improving student outcomes. Reformers can draw on this information as they use the framework. The following features appeared commonly across models and were associated with positive effects on student outcomes: personalized relationships with school staff members, increased academic rigor, teacher/student respect, teacher professional development, teacher/parent communication, principal leadership, and teacher mutual support. In reviewing their own efforts to strengthen high schools, policymakers and practitioners may want to consider seriously how they are addressing these aspects of the high school student experience.