The effectiveness of fenfluramine with hyperserotonergic autistic individuals (n=28 and ages 6-30) was evaluated. Evaluation of videotape recordings of individual behaviors suggested that fenfluramine failed to increase communicative behaviors or decrease stereotypic behaviors and inappropriate behaviors although a serotonergic effect was found in…

Individuals with developmental disability (n=400) were assessed with the "Dyskinesia Identification System: Condensed User Scale" (DISCUS), a 15-item tardive dyskinesia rating scale shortened from the "Dyskinesia Identification System-Coldwater." Based on interrater reliability, 2-week stability, and other analyses, DISCUS is…

Direct observational data were collected on the behavior of 26 elementary school-age boys with fragile X syndrome (FXS), the most prevalent inherited cause of mental retardation, during classroom academic activities. Findings indicated classroom engagement comparable to that of peers and not related to intrasubject variables such as severity of…

Assessment of 84 children diagnosed with controlled or uncontrolled complex partial or absence seizures but no documented learning or emotional disorders found no influence of seizure type on achievement test scores or behavioral ratings. A main effect was found for degree of control, with poorly controlled seizures correlating with lower reading…

This study compared the clinical efficacy of a dopaminergic antagonist (amisulpride) and a dopaminergic agonist (bromocriptine) with 9 children (ages 4-13) with autism and probable severe mental retardation. The amisulpride acted preferentially on specific autism symptoms and the bromocriptine on motor hyperactivity and attention symptoms.…