Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

This article explores the practical relevance of pragmatism as a research paradigm through the example of a piece of pragmatic research that not only used both quantitative and qualitative research methods but also exploited the inherent duality of the data analyzed. Thus, the article aims to make the case that pragmatism as a research paradigm…

To investigate the generalizability of the results of single-case experimental studies, evaluating the effect of one or more treatments, in applied research various simultaneous and sequential replication strategies are used. We discuss one approach for aggregating the results for single-cases: the use of hierarchical linear models. This approach…

Laboratory simulations combine the strengths of lab experiments and field studies while avoiding many of their liabilities. They permit the emotional involvement, the time needed for development of norms and interlocked systems of interaction, and the broad range of variables typical of field settings, yet allow for experimental controls and…

The target of difficulty of the Educational Technology Center (ETC) Heat and Temperature Group is basic thermal physics, particularly the differentiation between heat and temperature. High school teachers often find that thermal concepts are very difficult for their students to master and attribute students' difficulties at least in part to the…