Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

This article seeks to provide researchers and practitioners in laboratory education, particularly those involved in the curriculum design and implementation of teaching laboratories at university level, with a conceptual framework and a working model for an integrated assessment of learning domains, by attending to a more holistic approach to…

Describes the necking of polymer sheets that occurs when they are stretched. Discusses the effect and the mechanisms of necking. Lists four references. (YP)

Discusses the role of dogs in research, considering their use in studies related to: behavior; aging; anesthesia; gastrointestinal surgery; the brain; organ transplants; radiobiology; trauma and shock; arterial diseases; hemophelia; ophthalmology; diabetes; nutrition; cancer; lupus; cyclic neutropenia; thyroiditis; hepatitis; skeletal system,…

Investigates strategies of 10-year-olds and 14-year-olds in tasks requiring prospective memory. Subjects were instructed to perform activities after waiting 30 minutes. As predicted, strategic time-monitoring occurred more frequently in the home than in the laboratory. Emphasizes the power of the laboratory as a contrasting context for…

The importance of targeting certain stages in the life cycle of the virus for antiviral therapy is discussed with reference to the Human Immunodeficiency Virus type 1. Research conducted on a core antigen, p24, is described. (MSE)

The molecular properties of Human Immunodeficiency Virus type 1 (HIV-1) reverse transcriptase are summarized and several strategies developed to inhibit its activity are described. (MSE)

Discusses issues and the public's concerns related to using laboratory animals for research purposes. Indicates that several perceptions (such as recognizing that the public's attitudes toward respect for animal life are no more irrational than many broader attitudes toward the sacredness of life) characterize the most responsible of recent…

The Grignard reagent used in the laboratory synthesis of organic compounds is the product resulting from the reaction of an alkyl or aryl halide with elemental magnesium. Describes the structure, formation, and some reactions of the reagent. (YP)

Self-efficacy, or a person's perception of his/her own mastery of a skill, affects subsequent task performance and predictions of future performance. To examine older adults' metamemorial knowledge with respect to predicting their performance on everyday and laboratory memory tasks, 28 adults (22 females, 6 males), aged 58 to 80 years, completed a…

Reports an experiment for examining protein-ligand binding using the enzyme carbonic anhydrase. Describes the experimental procedures consisting of the syntheses of an azosulfonamide and its complex formation with carbonic anhydrase. (YP)

Provides guidelines for translating university science laboratories into middle school science activities. The need for guidelines is based on the authors' discovery that teachers teach what they were taught. Discusses six expected outcomes of middle school science activities: developing science concepts; practicing process skills; quantitative…

Describes experiments used during recent history to explain the nature of the quantum world. Explains the essential elements of experiments using polarized light and magnetic flux. Illustrates differences between classical theories in physics and quantum theory. Shows how experiments in the microscopic and macroscopic world appear to support…

This was an experiment to test the extended discretion laboratory approach versus a guided-inquiry approach for teaching biology in a university setting. Among three criterion variables (examination, reports, and quizzes), only the laboratory report scores showed differences between groups and group-by-instructor interaction. (Author/YP)

Discusses the characteristics and development of a computer simulation laboratory for educational administration research at the University of Wisconsin at Madison, and reviews an experimental study performed at the laboratory on stress in decision-making. Explores how simulations provide researchers access to experimental conditions unavailable…