ERIC Number: EJ780142
Record Type: Journal
Publication Date: 2007
Pages: 6
Abstractor: Author
ISBN: N/A
ISSN: ISSN-1470-8175
EISSN: N/A
Available Date: N/A
Web-Based Analysis for Student-Generated Complex Genetic Profiles
Kass, David H.; LaRoe, Robert
Biochemistry and Molecular Biology Education, v35 n6 p404-409 Nov-Dec 2007
A simple, rapid method for generating complex genetic profiles using Alu-based markers was recently developed for students primarily at the undergraduate level to learn more about forensics and paternity analysis. On the basis of the Cold Spring Harbor Allele Server, which provides an excellent tool for analyzing a single Alu variant, we present a new web-based system for analyzing several genetic loci, including Hardy-Weinberg equilibrium, genetic drift, and Fst genetic-distance calculations, as well as analyzing eight loci profiles simultaneously for forensic purposes. By analyzing several loci, students can determine more precisely the relatedness of populations as well as develop a greater appreciation for the use of DNA markers in forensic analysis by concurrently assessing the frequencies of genotypes for eight genetic loci. (Contains 6 figures and 1 footnote.)
Descriptors: Persuasive Discourse, Genetics, Profiles, Internet, Web Based Instruction, Computer Uses in Education, Undergraduate Students, College Science, Crime, Criminology
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Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: Students; Teachers
Language: English
Sponsor: National Science Foundation, Arlington, VA.
Authoring Institution: N/A
Grant or Contract Numbers: N/A
Author Affiliations: N/A