CRISPR-Cas9 is revolutionizing how we conduct scientific research, treat disease, and develop new crops. The widespread impact of this genome-editing technology makes it critical for undergraduate students to understand and engage with this new tool. In this article, we describe a multi-week lab module that teaches undergraduates how to design…

GENIQUEST is a cyberlearning computer program that allows students to investigate biological data using a research-based instructional model. In this article, the authors make the case for using cyberlearning to teach students about the rapidly growing fields of genomics and computational biology. (Contains 2 figures and 1 online resource.)

"BIO2010" put forth the goal of improving the mathematical educational background of biology students. The analysis and interpretation of microarray high-dimensional data can be very challenging and is best done by a statistician and a biologist working and teaching in a collaborative manner. We set up such a collaboration and designed a course on…

Discusses some of the major genetic information processes which may be modeled by computer program string manipulation, focusing on replication and transcription. Also discusses instructional applications of using string models. (JN)

The authors teach upper-level science courses in cell biology, genetics, and biochemistry at a public, four-year "community university" that serves a demographically diverse population of traditional and nontraditional students. In this article, they describe some of the issues they have found to be particularly significant at their "community…

In our Fundamentals of Genetics lab, students perform a wide variety of labs to reinforce and extend the topics covered in lecture. I developed an active-learning lab to augment the lecture topic of mutagenesis. In this lab exercise, students determine if a compound they bring from home is a mutagen. Students are required to read extensive…

Describes five computer programs: four simulations of genetic and physical mapping experiments and one interactive learning program on the genetic coding mechanism. The programs were originally written in BASIC for the VAX-11/750 V.3. mainframe computer and have been translated into Applesoft BASIC for Apple IIe microcomputers. (JN)

Reviewed are three computer software programs: the Astronomer (astronomy program for middle school students and older); Hands-on-Statistics: Explorations with a Microcomputer (statistics program for secondary school students and older); and CATGEN (a genetics program for secondary school students and older). Each review provides information on:…

Bioinformatics is one of the fastest growing scientific areas over the last decade. It focuses on the use of informatics tools for the organization and analysis of biological data. An example of their importance is the availability nowadays of dozens of software programs for genomic and proteomic studies. Thus, there is a growing field (private…

An interactive computer program in microbial genetics is described. The simulation allows students to work at their own pace and develop understanding of microbial techniques as they choose donor bacterial strains, specify selective media, and interact with demonstration experiments. Sample questions and outputs are included. (DH)

Describes a microcomputer program (written for the Apple II+) which can serve as a lecture demonstration aid in explaining genetic transcription and translation. The program provides unemotional information on student errors, thus serving as a review drill to supplement the classroom. Student participation and instructor options are discussed. (DH)

The educational design of a project option in an Open University course on evolution is described. Also described is the simulation which models the genetic and evolutionary consequences of two populations of a species of flowering plant coming together after a period of genetic isolation. (Author/JN)

Provides activities (and program listings) related to a Mendelian genetics experiment, Tetranacci numbers, and Pascal loops. Also suggests using the computer and spreadsheets to plan the production of a school yearbook. (JN)

We have developed an introductory bioinformatics exercise for sophomore biology and biochemistry students that reinforces the understanding of the structure of a gene and the principles and events involved in its expression. In addition, the activity illustrates the severe effect mutations in a gene sequence can have on the protein product.…

Reviews computer programs for simulating experiments on (1) polymer sequencing; (2) genetic codes; and (3) cloning. Reasons for using such software are provided. (DH)