Within the eukaryotic cell, the actin cytoskeleton is a crucial structural framework that maintains cellular form, regulates cell movement and division, and facilitates the internal transportation of proteins and organelles. External cues induce alterations in the actin cytoskeleton primarily through the activation of Rho GTPases, which then bind…

The Clemmensen reduction is a common example of a reaction demonstrating the deoxygenation of carbonyl groups, which is a topic that has been widely studied in the field of organic chemistry. The use of trimethylchlorosilane, as a substitute for concentrated hydrochloric acid, allows for the reduction of carbonyl groups. The Clemmensen reduction…

Although the teaching of mechanics at advanced K12 levels often starts with a brief introduction to physical quantities and units, the nature and function of measurements in physics and their inherent uncertainty are hardly ever discussed. The laboratory is mainly used to illustrate the theoretical principles taught in class. This paper presents a…

A laboratory sequence is described that is suitable for upper-level biochemistry or molecular biology laboratories that combines project-based and traditional laboratory experiments. In the project-based sequence, the individual laboratory experiments are thematically linked and aim to show how a bacterial antibiotic sensing noncoding RNA (the…

To enhance critical thinking and problem-solving skills, a project-based learning (PBL) approach for "Instrumental Techniques" courses in undergraduate physical chemistry was specifically developed for a pharmacy bachelor degree program. The starting point of this PBL was an open-ended question that is close to the student scientist's…

This paper discusses laboratory activities that can improve the meaningfulness of natural product chemistry course. These laboratory activities can be useful for students from many different disciplines including chemistry, pharmacy, and medicine. Students at the third-year undergraduate level of chemistry education undertake the project to…

The laboratory unit demonstrates a project based approach to teaching physical chemistry laboratory where upper-division undergraduates carry out a transient-absorption experiment investigating the kinetics of cis-trans isomerization of N,N-dimethyl-4,4'-azodianiline. Students participate in modification of a standard flash-photolysis spectrometer…

The determination of kinetic data is central to reaction mechanism; science courses usually include experiments on chemical kinetics. Thanks to PC-controlled data acquisition and availability of software, the students calculate rate constants, whether the experiment has been done properly or not. This contrasts with their experience in, e.g.,…

A drug discovery project has been successfully implemented in a first-year general, organic, and biochemistry (GOB) health science course and second-year organic undergraduate chemistry course. This project allows students to apply the fundamental principles of chemistry and biology to a problem of medical significance, practice basic laboratory…

This paper is intended for engineering educators, high school curriculum designers, and high school teachers interested in integrating authentic, project-based learning experiences into their classes. These types of projects may appear complex, but have many advantages. We characterize the successful implementation of one such project, the…

This paper presents an original undergraduate student project in theoretical mechanics: a demonstration of theory and experiment agreement inspired by a recently theoretically treated mechanical problem of coupled rolling motion of two cylinders. The problem of a mechanical system subjected to non-holonomic constraints is theoretically and…

Employment of a data-acquisition system for data collection and calculations makes experiments with antennas more convenient and less time consuming. The determined directional patterns of the dipole antennas of different lengths are in reasonable agreement with theory. The enhancement of the signal by using a reflector is demonstrated, and a…

In this experiment, organic chemistry students perform reactions between three naphthyl acetate derivatives and the diazonium salt Fast-Red TR, under basic conditions. The three naphthyl acetate derivatives used in this study are 2-naphthyl acetate (1a), 6-bromo-2-naphthyl acetate (1b) and 1,6-dibromo-2-naphthyl acetate (1c). The two-step, one-pot…

A magnetically controlled pendulum is used for observing free and forced oscillations, including nonlinear oscillations and chaotic motion. A data-acquisition system stores the data and displays time series of the oscillations and related phase plane plots, Poincare maps, Fourier spectra and histograms. The decay constant of the pendulum can be…

Here, we describe a laboratory experiment as part of an upper-level vertebrate physiology course for biology majors to investigate the physiological response of vertebrates to osmoregulatory challenges. The experiment involves measuring plasma osmolality and Na[superscript +] -K[superscript +] -ATPase activity in gill tissue of teleost fish…