This curriculum represents the current approach to prevention education about sexually transmitted diseases (STD) for students in grades 7-12, combining health messages about STD, including HIV/AIDS, into one curriculum. The instructor's guide discusses adolescents' need for STD/HIV prevention education; presents information about the effectiveness of STD prevention and goals and implementation strategies for school STD/HIV prevention education; and offers and selected information resources. Two lesson plans (one for five sessions and one for eight sessions) are presented. Next, the manual highlights 19 learning opportunities (e.g., identifying STD/HIV issues, dating and avoiding STD/HIV, resisting negative peer pressure, STD/HIV support and help sources, and Internet STD/HIV advice council). The learning opportunities are intended to reinforce the health-enhancing attitudes, behaviors, and skills emphasized in the student manual. The final section presents five types of test questions: true/false, multiple choice, short answer, essay, and life situations. Two appendixes offer handouts (sources of STD/HIV help, STD/HIV summary sheet, and guidelines for correct condom use) and worksheets (e.g., identifying STD/HIV issues, spread of STD/HIV opinion, choosing abstinence, and barriers to condom use). (SM)