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Pharmacotherapy Adherence for Pediatric Anxiety Disorders: Predictors and Relation to Child Outcomes
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Zehgeer, Asima; Ginsburg, Golda S.; Lee, Phyllis; Birmaher, Boris; Walkup, John; Kendall, Philip C.; Sakolsky, Dara; Peris, Tara – Child & Youth Care Forum, 2018
Background: Pharmacotherapy is considered an evidenced-based treatment for anxious youth. There is a need to better understand the relation between medication adherence and child outcomes. Objective: This study prospectively examined: (1) baseline predictors of adherence and (2) the relation between medication adherence and clinical outcomes in…
Descriptors: Drug Therapy, Anxiety, Adolescents, Correlation
Impact of Treatments for Depression on Comorbid Anxiety, Attentional, and Behavioral Symptoms in Adolescents with Selective Serotonin Reuptake Inhibitor-Resistant Depression
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Hilton, Robert C.; Rengasamy, Manivel; Mansoor, Brandon; He, Jiayan; Mayes, Taryn; Emslie, Graham J.; Porta, Giovanna; Clarke, Greg N.; Wagner, Karen Dineen; Birmaher, Boris; Keller, Martin B.; Ryan, Neal; Shamseddeen, Wael; Asarnow, Joan Rosenbaum; Brent, David A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: To assess the relative efficacy of antidepressant medication, alone and in combination with cognitive behavioral therapy (CBT), on comorbid symptoms of anxiety, attention, and disruptive behavior disorders in participants in the Treatment of Resistant Depression in Adolescents (TORDIA) trial. Method: Adolescents with selective serotonin…
Descriptors: Behavior Disorders, Attention Deficit Hyperactivity Disorder, Adolescents, Anxiety Disorders
Social Interpretation Bias in Children and Adolescents with Anxiety Disorders: Psychometric Examination of the Self-Report of Ambiguous Social Situations for Youth (SASSY) Scale
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Gonzalez, Araceli; Rozenman, Michelle; Langley, Audra K.; Kendall, Philip C.; Ginsburg, Golda S.; Compton, Scott; Walkup, John T.; Birmaher, Boris; Albano, Anne Marie; Piacentini, John – Child & Youth Care Forum, 2017
Background: Anxiety disorders are among the most common mental health problems in youth, and faulty interpretation bias has been positively linked to anxiety severity, even within anxiety-disordered youth. Quick, reliable assessment of interpretation bias may be useful in identifying youth with certain types of anxiety or assessing changes on…
Descriptors: Anxiety Disorders, Psychometrics, Ambiguity (Context), Factor Analysis
Sleep Items in the Child Behavior Checklist: A Comparison with Sleep Diaries, Actigraphy, and Polysomnography
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Gregory, Alice M.; Cousins, Jennifer C.; Forbes, Erika E.; Trubnick, Laura; Ryan, Neal D.; Axelson, David A.; Birmaher, Boris; Sadeh, Avi; Dahl, Ronald E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: The Child Behavior Checklist is sometimes used to assess sleep disturbance despite not having been validated for this purpose. This study examined associations between the Child Behavior Checklist sleep items and other measures of sleep. Method: Participants were 122 youth (61% female, aged 7 through 17 years) with anxiety disorders…
Descriptors: Anxiety Disorders, Check Lists, Sleep, Child Behavior
Remission after Acute Treatment in Children and Adolescents with Anxiety Disorders: Findings from the CAMS
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Ginsburg, Golda S.; Kendall, Philip C.; Sakolsky, Dara; Compton, Scott N.; Piacentini, John; Albano, Anne Marie; Walkup, John T.; Sherrill, Joel; Coffey, Kimberly A.; Rynn, Moira A.; Keeton, Courtney P.; McCracken, James T.; Bergman, Lindsey; Iyengar, Satish; Birmaher, Boris; March, John – Journal of Consulting and Clinical Psychology, 2011
Objective: To report on remission rates in anxious youth who participated in the Child/Adolescent Anxiety Multimodal Study (CAMS). The CAMS, a multisite clinical trial, randomized 488 children and adolescents (ages 7-17 years; 79% Caucasian; 50% female) with separation, social, and/or generalized anxiety disorder to a 12-week treatment of…
Descriptors: Anxiety Disorders, Evaluators, Cognitive Restructuring, Adolescents
Defining Treatment Response and Remission in Child Anxiety: Signal Detection Analysis Using the Pediatric Anxiety Rating Scale
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Caporino, Nicole E.; Brodman, Douglas M.; Kendall, Philip C.; Albano, Anne Marie; Sherrill, Joel; Piacentini, John; Sakolsky, Dara; Birmaher, Boris; Compton, Scott N.; Ginsburg, Golda; Rynn, Moira; McCracken, James; Gosch, Elizabeth; Keeton, Courtney; March, John; Walkup, John T. – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: To determine optimal Pediatric Anxiety Rating Scale (PARS) percent reduction and raw score cut-offs for predicting treatment response and remission among children and adolescents with anxiety disorders. Method: Data were from a subset of youth (N = 438; 7-17 years of age) who participated in the Child/Adolescent Anxiety Multimodal Study…
Descriptors: Rating Scales, Anxiety Disorders, Raw Scores, Child Health
Academic Impairment and Impact of Treatments among Youth with Anxiety Disorders
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Nail, Jennifer E.; Christofferson, Jennifer; Ginsburg, Golda S.; Drake, Kelly; Kendall, Philip C.; McCracken, James T.; Birmaher, Boris; Walkup, John T.; Compton, Scott N.; Keeton, Courtney; Sakolsky, Dara – Child & Youth Care Forum, 2015
Background: Global academic difficulties have often been reported in youth with anxiety disorders, however, little is known about the specific academic deficits in this population. Objective: To (a) evaluate the prevalence of seven specific academic impairments in children and adolescents with anxiety disorders, (b) determine whether these…
Descriptors: Anxiety Disorders, Children, Adolescents, Racial Differences
Clinical, Demographic, and Familial Correlates of Bipolar Spectrum Disorders among Offspring of Parents with Bipolar Disorder
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Goldstein, Benjamin I.; Shamseddeen, Wael; Axelson, David A.; Kalas, Cathy; Monk, Kelly; Brent, David A.; Kupfer, David J.; Birmaher, Boris – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Despite increased risk, most offspring of parents with bipolar disorder (BP) do not manifest BP. The identification of risk factors for BP among offspring could improve preventive and treatment strategies. We examined this topic in the Pittsburgh Bipolar Offspring Study (BIOS). Method: Subjects included 388 offspring, ages 7-17 years,…
Descriptors: Mental Disorders, Risk, Children, Adolescents
Objective Sleep in Pediatric Anxiety Disorders and Major Depressive Disorder
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Forbes, Erika E.; Bertocci, Michele A.; Gregory, Alice M.; Ryan, Neal D.; Axelson, David A.; Birmaher, Boris; Dahl, Ronald E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to examine sleep problems encountered in anxiety and depressive disorders among children and adolescents is conducted. Results indicated subjective and objective sleep problems in children and adolescents with anxiety disorders and need to be kept in mind when treating young anxious people.
Descriptors: Sleep, Adolescents, Children, Anxiety
Reward-Related Decision-Making in Pediatric Major Depressive Disorder: An fMRI Study
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Forbes, Erika E.; Christopher May, J.; Siegle, Greg J.; Ladouceur, Cecile D.; Ryan, Neal D.; Carter, Cameron S.; Birmaher, Boris; Axelson, David A.; Dahl, Ronald E. – Journal of Child Psychology and Psychiatry, 2006
Background: Although reward processing is considered an important part of affective functioning, few studies have investigated reward-related decisions or responses in young people with affective disorders. Depression is postulated to involve decreased activity in reward-related affective systems. Methods: Using functional magnetic resonance…
Descriptors: Anxiety Disorders, Brain, Rewards, Probability
Processing Emotional Facial Expressions Influences Performance on a Go/NoGo Task in Pediatric Anxiety and Depression
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Ladouceur, Cecile D.; Dahl, Ronald E.; Williamson, Douglas E.; Birmaher, Boris; Axelson, David A.; Ryan, Neal D.; Casey, B. J. – Journal of Child Psychology and Psychiatry, 2006
Background: This study investigated whether processing emotionally salient information such as emotional facial expressions influences the performance on a cognitive control task in pediatric anxiety and depression. Methods: The sample included 68 participants between 8 and 16 years of age selected into three diagnostic groups: Anxiety Disorder…
Descriptors: Anxiety Disorders, Nonverbal Communication, Depression (Psychology), Anxiety
Increased Error-Related Negativity (ERN) in Childhood Anxiety Disorders: ERP and Source Localization
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Ladouceur, Cecile D.; Dahl, Ronald E.; Birmaher, Boris; Axelson, David A.; Ryan, Neal D. – Journal of Child Psychology and Psychiatry, 2006
Background: In this study we used event-related potentials (ERPs) and source localization analyses to track the time course of neural activity underlying response monitoring in children diagnosed with an anxiety disorder compared to age-matched low-risk normal controls. Methods: High-density ERPs were examined following errors on a flanker task…
Descriptors: Evidence, Anxiety Disorders, Anxiety, Diagnostic Tests
Altered Emotional Processing in Pediatric Anxiety, Depression, and Comorbid Anxiety-Depression.
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Ladouceur, Cecile D.; Dahl, Ronald E.; Williamson, Douglas E.; Birmaher, Boris; Ryan, Neal D.; Casey, B.J. – Journal of Abnormal Child Psychology, 2005
The goal of this study was to examine some of the mechanisms underlying emotion regulation in childhood affective disorders by examining the impact of distracting emotional information during performance on a working memory task ("Emotional n-back" or E-n-back). The sample included 75 children (38 girls and 37 boys) between 8 and 16 years of age…
Descriptors: Memory, Depression (Psychology), Anxiety
Fluoxetine for the Treatment of Childhood Anxiety Disorders: Open-Label, Long-Term Extension to a Controlled Trial
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Clark, Duncan B.; Birmaher, Boris; Axelson, David; Monk, Kelly; Kalas, Catherine; Ehmann, Mary; Bridge, Jeffrey; Wood, D. Scott; Muthen, Bengt; Brent, David – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To assess the efficacy of fluoxetine for the long-term treatment of children and adolescents with anxiety disorders, including generalized anxiety disorder, separation anxiety disorder, and/or social phobia. Method: Children and adolescents (7-17 years old) with anxiety disorders were studied in open treatment for 1 year after they…
Descriptors: Psychiatry, Adolescents, Children, Separation Anxiety
Clinical Presentation and Course of Depression in Youth: Does Onset in Childhood Differ from Onset in Adolescence?
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Birmaher, Boris; Williamson, Douglas E.; Dahl, Ronald E.; Axelson, David A.; Kaufman, Joan; Dorn, Lorah D.; Ryan, Neal D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To simultaneously and prospectively compare the clinical presentation, course, and parental psychiatric history between children and adolescents with major depressive disorder. Method: A group of prepubertal children (n = 46) and postpubertal adolescents (n = 22) were assessed with structured interviews for psychopathology and parental…
Descriptors: Psychiatry, Psychopathology, Adolescents, Anxiety
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