One way to meet the unique challenges in diverse classrooms is co-teaching. Friend and Cook (2010) described co-teaching as an approach that provides specialized services to individual students in a general education classroom. Specifically, co-teaching involves two or more educators working collaboratively to deliver instruction to a heterogeneous group of students in a shared instructional space. This article describes co-teaching, an increasingly popular instructional delivery option for diverse classrooms. It provides an overview of co-teaching, highlights effective practices by two middle school co-teachers, and presents reflections about the effectiveness of co-taught classes from middle grades students. (Contains 3 figures.)