The purpose of this study was to investigate university students' perceptions of social media as a learning resource (SM-LR) in China and the USA in terms of their attitudes, perceived usefulness and behavioral intentions. An instrument used for this study was adapted from a prior validated survey based on the Technology Acceptance Model. The sample population consisted of 241 respondents from universities in China and the USA. The results suggested that most respondents (>75%) from each nation had used social media for learning purposes and that they shared similar understandings and definitions of social media. However, significant differences by nation were found concerning students' attitudes, perceived usefulness and behavioral intentions. Most respondents from China were more positive about SM-LR than their counterparts from the USA. Also, respondents who had previously used social media for learning were more positive about SM-LR. No correlations were found between students' self-reported academic performance and their attitudes, perceived usefulness, or behavioral intentions. Proposed areas of future research are discussed.