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Direct linkFoy, Michael R.; Akopian, Garnik; Thompson, Richard F. – Learning & Memory, 2008
Ovarian hormones influence memory formation by eliciting changes in neural activity. The effects of various concentrations of progesterone (P4) on synaptic transmission and plasticity associated with long-term potentiation (LTP) and long-term depression (LTD) were studied using in vitro hippocampal slices. Extracellular studies show that the…
Descriptors: Depression (Psychology), Memory, Neurological Organization, Brain
Weeks, Andrew C. W.; Connor, Steve; Hinchcliff, Richard; LeBoutillier, Janelle C.; Thompson, Richard F.; Petit, Ted L. – Learning & Memory, 2007
Eye-blink conditioning involves the pairing of a conditioned stimulus (usually a tone) to an unconditioned stimulus (air puff), and it is well established that an intact cerebellum and interpositus nucleus, in particular, are required for this form of classical conditioning. Changes in synaptic number or structure have long been proposed as a…
Descriptors: Stimuli, Classical Conditioning, Eye Movements, Animals
Thompson, Richard F.; Robleto, Karla; Poulos, Andrew M. – Learning & Memory, 2004
It is well established that the cerebellum and its associated circuitry are essential for classical conditioning of the eyeblink response and other discrete motor responses (e.g., limb flexion, head turn, etc.) learned with an aversive unconditioned stimulus (US). However, brain mechanisms underlying extinction of these responses are still…
Descriptors: Classical Conditioning, Neurological Organization, Perceptual Motor Learning, Behavioral Science Research
