Developed for use primarily with middle school age students, this introductory booklet provides a sample of innovative activities that integrate mathematics skills with science processes. The investigations employ a wide variety of readily available and easily understood materials. The 25 activities are sequenced from simple to complex according to the science processes of: (1) observing and classifying; (2) measuring; (3) estimating, predicting, and hypothesizing; (4) controlling variables; (5) gathering and recording data; (6) interpreting data; and (7) applying and generalizing. Each activity consists of student sheets and a teacher's guide. The teacher's guide contains background information and suggestions for classroom management, instruction, discussion, and program extension. (ML)