Four computer programs using the general purpose multiple linear regression program have been developed. Setwise regression analysis is a stepwise procedure for sets of variables; there will be as many steps as there are sets. Covarmlt allows a solution to the analysis of covariance design with multiple covariates. A third program has three solutions to the two-way disproportionate analysis of variance: (a) the method of fitting constants, (b) the hierarchical model and (c) the unadjusted main effects solution. The fourth program yields three solutions to the two-way analysis of covariance, with or without proportionality, and with multiple covariates. The three solutions are similar to those described for a two-way analysis of variance with disproportionate cell frequencies. (Author)