Teaching the three-dimensional structure of saccharides has consistently been a challenging aspect of organic chemistry courses, impeding students' ability to grasp more advanced topics in biochemistry and food chemistry. In this article, we designed and developed a novel d-glucopyranose model using 3D printing technology for the first time. This…

A mixture of salt water and isopropyl alcohol is immiscible, forming two separate liquids with the organic layer on top and aqueous layer on bottom. When universal indicator is added to such a mixture, all of the indicator compounds in the universal indicator preferentially dissolve in the alcohol--except for phenolphthalein at high pH. Mixtures…

The great development of high-throughput molecular biology techniques and the consequent generation of massive data have made Bioinformatics essential for undergraduate Bioscience students. The importance of this scientific discipline is evidenced by the huge number of specialized publications, tools, and databases available. Training in…

The use of molecular models in chemistry and biochemistry classes is very effective in helping students understand covalent bonds and the chemical structure of molecules. However, conventional molecular models cannot represent intermolecular interactions such as hydrogen bonds and electrostatic interactions. Herein, we describe 3D printed…

Understanding the general ideas and methods of detecting molecular structures is essential in high school chemistry. However, there is a need for more practical activities in teaching. A hands-on activity was designed in this study, which uses flexible foam balls and long sticks such as knitting needles to imitate how scientists construct the 3D…

The initial learning experience is a critical opportunity to support conceptual understanding of abstract STEM concepts. Although hands-on activities and physical three-dimensional models are beneficial, they are seldom utilized and are replaced increasingly by digital simulations and laboratory exercises presented on touchscreen tablet computers.…

A straightforward protocol for the preparation of the colorful and air-stable diphenyl ditelluride is described. In one laboratory session, students isolate their product and characterize it via melting point determination, mass spectrometry, and NMR spectroscopy ([superscript 1]H, [superscript 13]C­{[superscript 1]H}, and [superscript…

Chemistry undergraduate curricula typically place Nuclear Magnetic Resonance (NMR) lectures under either Organic Chemistry or Spectroscopy courses, aiming for students to acquire basic knowledge for the determination of the structure of simple organic compounds. On the other hand, regarding laboratory practice, NMR is frequently disregarded by…

The main difficulty in studying molecular symmetry is the mental manipulation of molecules when searching for symmetry. Numerous methods of teaching molecular symmetry require students to identify symmetry elements of objects or molecules. As an alternative, we propose activity that identifies symmetry using elements outside the objects, together…

The impact of an interactive in-class Valence-Shell Electron-Pair Repulsion (VSEPR) activity, designed and implemented by the author in her first-year undergraduate chemistry classes, was assessed through the statistical analysis of pre- and posttreatment quizzes on VSEPR theory and the analysis of questionnaires. The activity consisted of…

This report outlines an approach for preparing 5-color 3D printed plastic models of molecular orbitals and electron density surfaces using a hobby-grade 3D printer. Instructions are provided for preparing 3D orbital and electron density surface (EDS) models using solid or mesh representations in ground state and transition state structures. We…

In undergraduate science education, laboratory courses stand as essential cornerstones of experiential learning. Chemistry laboratory courses offer students unique hands-on experiences that bridge the gap between theoretical knowledge and practical application. The journey through the undergraduate chemistry curriculum is paved with a series of…

A comprehensive laboratory-style teaching activity involving the synthesis, characterization, and analysis of structure-activity relationships of metal-organic framework (MOF) nanozymes was developed specifically for undergraduates at Tianjin University. The students acquired familiarity with the general approach in synthesizing MOFs by…

Having a deeper understanding of molecules in their structural forms allows students to grasp biochemical and general chemical concepts in a more profound manner. Through the use of visualization software, we have shown that students gain confidence and insight into the chemical workings of molecular structure and can then utilize this knowledge…

Nanotechnology has been recognized as an important driver of the future economy, and so nanoscience is increasingly being incorporated into the undergraduate chemistry curriculum. This experiment includes the chemical synthesis, optical and chemical testing, and microscopic imaging of gold nanoparticles. Since nanoparticles are too small to…