Accelerated longitudinal designs (ALDs) provide an opportunity to capture long developmental periods in a shorter time framework using a relatively small number of assessments. Prior literature has investigated whether univariate developmental processes can be characterized with data obtained from ALDs. However, many important questions in…

This study examined how timing (i.e., relative maturity) and rate (i.e., how quickly infants attain proficiency) of A-not-B performance were related to changes in brain activity from age 6 to 12 months. A-not-B performance and resting EEG (electroencephalography) were measured monthly from age 6 to 12 months in 28 infants and were modeled using…

The formation of mate recognition memory in mice is associated with neural changes at the reciprocal dendrodendritic synapses between glutamatergic mitral cell (MC) projection neurons and GABAergic granule cell (GC) interneurons in the accessory olfactory bulb (AOB). Although noradrenaline (NA) plays a critical role in the formation of the memory,…

An anaphoric reference to the complement-set is a reference to the set that does not fulfil the predicate of the preceding sentence. Preferred reference to the complement-set has been found in eye movements when a character's implicit desire for a high amount has been denied using a negative emotion. We recorded event-related potentials to examine…

NMDA receptors (NMDARs) are considered critical for the consolidation of extinction but recent work challenges this assumption. Namely, NMDARs are not required for extinction retention in infant rats as well as when extinction training occurs for a second time (i.e., reextinction) in adult rats. In this study, a possible third instance of…

The present study addresses word recognition automaticity in Spanish-speaking adults who are neoliterate by assessing the event-related potential N170 for word stimuli. Participants engaged in two reading conditions that vary the degree of attention required for linguistic components of reading: (a) an implicit reading task, in which they detected…

Word learning from linguistic context is essential for vocabulary growth from grade school onward; however, little is known about the mechanisms underlying successful word learning in children. Current methods for studying word learning development require children to identify the meaning of the word after each exposure, a method that interacts…

Creative objects differ from ordinary objects in that they are created by human beings to contain novel, creative information. Previous research has demonstrated that ordinary object processing involves both a perceptual process for analyzing different features of the visual input and a higher-order process for evaluating the relevance of this…

This work examines the link between low-level cortical acoustic processing and higher-level cortical phonemic processing. Specifically, using functional magnetic resonance imaging, it looks at 1) whether or not the vowels [alpha] and [i] are distinguishable in regions of interest defined by the first two resonant frequencies (formants) of those…

Development and sex differentiation impart an organizational influence on the neuroanatomy and behavior of mammalian species. Prior studies suggest that brain regions associated with fear motivated defensive behavior undergo a protracted and sex-dependent development. Outside of adult animals, evidence for developmental sex differences in…

Pain assessments typically depend on self-report of the pain experience. Yet, in individuals with autism spectrum disorders, this can be an unreliable due to communication difficulties. Importantly, observations of behavioral hypo- and hyperresponsivity to pain suggest altered pain sensitivity in autism spectrum disorder. Neuroimaging may provide…

Previous research has demonstrated that areas in the medial temporal lobe and prefrontal cortex (PFC) show increased activation during retrieval of overlapping sequences. In this study, we designed a task in which degree of overlap varied between conditions in order to parse out the contributions of hippocampal and prefrontal subregions as overlap…

The hypothesis that brain activity may differ during varied types of video game play was investigated in two studies of event-related potentials exhibited by children age 7 to 12 when processing game-based stimuli requiring correct/incorrect responses or choices between two imaginative alternative responses. The first study had 22 children of…

The present study meta-analyzed 45 experiments with 959 subjects and 463 activation foci reported in 43 published articles that investigated the neural mechanism of moral functions by comparing neural activity between the moral task conditions and non-moral task conditions with the Activation Likelihood Estimation method. The present study…

The serine protease inhibitor neuroserpin regulates the activity of tissue-type plasminogen activator (tPA) in the nervous system. Neuroserpin expression is particularly prominent at late stages of neuronal development in most regions of the central nervous system (CNS), whereas it is restricted to regions related to learning and memory in the…