The aim of this study was to examine genetic variations underlying the early neurodevelopmental outcome of developmental disabilities (DDs). The study cohort consisted of 191 children with DDs. Diagnosis was assessed at baseline and at the index age (72-84 months). Exome sequencing was conducted and putative risk variants were identified.…

Quality rating and improvement systems (QRISs) are designed to assess, improve, and communicate the quality of early care and education programs. Using administrative data, we investigated whether providers that participated in a county-level QRIS saw increases to their global quality (tier) rating, domain-specific quality ratings, and scores on…

Global access to preschool has increased dramatically yet preschool quality is often poor. We use a randomized controlled trial to evaluate two approaches to improving the quality of Colombian preschools. We find that the first, which was rolled out nationwide and provides additional resources for materials and new staff, did not benefit…

This research brief is one of a series of six briefs, which provide an overview of available evidence shown in the Campbell-UNICEF Mega-Map of the effectiveness of interventions to improve child well-being in low- and middle-income countries. Five of these briefs summarize evidence as mapped against the five goal areas of UNICEF's 2018-2021…

Today millions of children are trapped in situations of war, conflict, violence and displacement. Science shows that violence has a detrimental effect on the development of young children. It, also, heralds in a new era, with opportunities to contribute to sustaining peace and prevention of violence, through investment in early childhood…

This Self-Study Guide has been developed to support Florida Voluntary Prekindergarten Providers (VPK) who are required to complete an improvement plan process (i.e., low-performing providers). The guide has sections that can be used during both the process of selecting target areas for an improvement plan and the process of implementing new or…

"The demographics of families in poverty around the globe may be diverse, but parents' dreams for their children are similar everywhere: good health, a good education, economic stability, and a better future." This new report from the Bernard van Leer Foundation and Ascend at The Aspen Institute develops a "two generation"…

Early childhood is a crucial stage in a child's life, and aspects of the environment in the physical, social-emotional, cognitive, and health and safety domains all play important roles in shaping children's development during these early years. Having a valid and reliable measure of the quality of these aspects of children's care settings is…

Early Childhood Comprehensive Systems (ECCS) grants help states and communities improve early childhood systems to support child development, equitable access to quality services and supports, and family well-being. Truly interdisciplinary, ECCS promotes cross-sector systems change initiatives that focus on integrating health care, mental health,…

Over 5 million American children under the age of 18 years, a disproportionate number of whom are Black or Latino, have had a residential parent jailed or incarcerated. While a number of existing studies identify parental incarceration as a key risk factor for poor child and family outcomes, there is more limited information describing programs…

The quality of early care and education affects a wide range of children's experiences and developmental outcomes. Family Child Care (FCC) is no exception, and attention to increasing the quality of Family Child Care is needed. The purpose of the current study was to examine an experimental case of intensive Professional Development (PD) in FCC…

The "Integrated Approaches to Supporting Child Development and Improving Family Economic Security" project was conducted by Mathematica Policy Research and Northwestern University for the Office of Planning, Research and Evaluation (OPRE), in the Administration for Children and Families (ACF) at the U.S. Department of Health and Human…

Home visitation programs are designed to provide comprehensive services that promote parent's abilities to create stable, nurturing care environments for their children. In order for program goals to be met, parents must participate actively and be engaged with the programs' mission. However, promoting engagement and participation are complex…

Based on Laura Colker, Derry Koralek, and Diane Trister Dodge's classic book, originally published by NAEYC in 1993, High-Quality Early Childhood Programs offers detailed descriptions of what one should see in high-quality programs (and why) to provide a strong foundation of child development knowledge and principles translated into practice.…

This is the executive summary for the report, "From Best Practices to Breakthrough Impacts: A Science-Based Approach to Building a More Promising Future for Young Children and Families." Early childhood is a time of great promise and rapid change, when the architecture of the developing brain is most open to the influence of…