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Mitchell, Julia R.; Trettel, Sean G.; Li, Anna J.; Wasielewski, Sierra; Huckleberry, Kylie A.; Fanikos, Michaela; Golden, Emily; Laine, Mikaela A.; Shansky, Rebecca M. – Learning & Memory, 2022
Pavlovian fear conditioning is a widely used behavioral paradigm for studying associative learning in rodents. Despite early recognition that subjects may engage in a variety of both conditioned and unconditioned responses, the last several decades have seen the field narrow its focus to measure freezing as the sole indicator of conditioned fear.…
Descriptors: Fear, Animals, Gender Differences, Responses
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Amorim, Felippe E.; Chapot, Renata L.; Chapot, Renata L.; Lee, Jonathan L. C.; Amaral, Olavo B. – Learning & Memory, 2021
Remembering is not a static process: When retrieved, a memory can be destabilized and become prone to modifications. This phenomenon has been demonstrated in a number of brain regions, but the neuronal mechanisms that rule memory destabilization and its boundary conditions remain elusive. Using two distinct computational models that combine…
Descriptors: Memory, Brain Hemisphere Functions, Biochemistry, Behavior Patterns