Resonance is a fundamental chemistry concept first introduced to students in General Chemistry I, reintroduced in Organic Chemistry I, and then utilized throughout other higher-level chemistry courses. A molecule or ion can be said to exhibit resonance when it can be represented by two or more chemical structures (i.e., Lewis structures) that…

The concepts of electronegativity and classical electronegativity scales are briefly described. Electronegativity scales have practical quantitative applications, and this work suggests activities which can assist students select the scales for use in chemistry applications. It provided examples of the use of an appropriate electronegativity…

This review describes a computational chemistry exercise aimed at enhancing the understanding of upper-division undergraduates in organic chemistry and physical chemistry regarding the structures and aromaticities of cyclobutadiene and cyclooctatetraene. This exercise exposes students to chemical problems that require computational methods as a…

Studies investigating chemistry students' understanding of intermolecular forces have listed alternative conceptions; however, there is a call to investigate why students might have these alternative conceptions. This study describes how second semester general chemistry students predict the location of dipole-dipole forces between two molecules…

The subject of pharmaceutical research has traditionally focused on drugs with systemic effects. However, contemporary approaches aspire to achieve targeted drug delivery, with the aim of combatting infections with a precise immune response. Active substances are encapsulated in nanoparticles, transported through the body, and selectively released…

Resonance is a foundational organic chemistry concept, but it is consistently misunderstood by undergraduate students. The development of a concept inventory--a multiple-choice assessment where the incorrect answer choices stem from commonly held alternate conceptions--on the concept of resonance could help organic chemistry instructors quickly…

Understanding reaction mechanisms is integral to success in organic chemistry; however, prior research suggests that learners struggle with recognizing the importance of underlying implicit features in reaction mechanisms. Because of this struggle, understanding how learners' reason about reaction mechanisms and developing assessments to elicit…

A virtual Game-Based Tournament of Chemistry was developed as an alternative to the traditional problem-solving classes to aid students in reviewing and understanding organic acidity and basicity concepts. The tournament was based on a multilingual virtual board game (English, Portuguese, French, and Italian) which aimed to facilitate students'…

Keto-enol tautomerization is paramount to understanding the mechanisms involved in many organic reactions and biochemical transformations. Isomerization of an enol to a carbonyl compound is typically introduced during the discussion of the acid-catalyzed electrophilic addition of water to alkynes. The tautomerization of carbonyl compounds to enol…

Molecules and Computer: Chemistry Calculations in Class (MC[superscript 4]) is a computational laboratory intended for final-year high school or undergraduate students. The topic is the antioxidant potential of anthocyanidins, which is chemically related to their radical scavenging action via the mechanism of hydrogen atom transfer (HAT). This…

Chirality continues to intrigue scientists because of its implications in various scientific areas, including the long-unsolved question of its development and link with the origin of life. Chirality plays a significant role in medicine with the advent of chiral drugs and the consequent importance of asymmetric synthesis. For many undergraduate…

Molecular representations that show chemical bonding are ubiquitous in general and organic chemistry. These help in communicating chemistry concepts that are fundamental to understanding "how" and "why" molecules interact. The goal of this dissertation work is to offer an evidence-based report on the affordances and limitations…

An exciting recent development in chemistry has been the ability to control nanoparticle crystal morphology or shape. Nanoparticles of different shapes present different crystal surfaces (or facets) with respect to the surrounding environment. Synthetic control over nanoparticle morphology has enabled the study of the influence of surface facets…

The learners' conceptual understanding has become one of the leading research areas conducted by educational researchers. Both students and current educators should actively work to improve their understanding of alternative conceptions and deepen their conceptual knowledge. One of the essential concepts in chemistry learning is colligative…

Education in organic chemistry is highly reliant on molecular representations. Students abstract information from representations to make sense of submicroscopic interactions. This study investigates relationships between differing representations: bond-line structures, ball-and-stick, or electrostatic potential maps (EPMs), and predicting partial…