Objective: In this study, to investigate the place of T cell-mediated immunity in the etiology of ADHD, for which we do not have enough information; we aimed to investigate the activity of DPP IV and ADA, which are T cell-related enzymes, and the relationship of these enzymes with ADHD symptoms in children with ADHD. Methods: Twenty-seven children…

Increasing evidence highlights the role of disrupted circadian rhythms in the neural dysfunctions and sleep disturbances observed in autism spectrum disorder and attention-deficit/hyperactivity disorder. However, the causality and directionality of these associations remain unclear. In this study, we employed a bidirectional two-sample Mendelian…

The current study examined how individuals with neurodevelopmental disorders navigate the complexities of learning within multidimensional environments marked by uncertain dimension values and without explicit guidance. Participants engaged in a game-like complex reinforcement learning task in which the stimuli dimension determining reward…

Objective: Neurotypical individuals can prioritize particularly valuable information in working memory. This is a well-replicated effect, demonstrated across a wide variety of task factors and age groups. However, it is not clear if individuals with symptoms of ADHD are able to do this effectively, as there is some evidence this group struggle to…

Objective: Maladaptive daydreaming (MD) is an impairing condition characterized by addiction to narrative, emotional fantasizing, involving dissociative absorption. By compulsively withdrawing toward vivid imaginative scenarios, MD hinders attentional functioning and replaces social interactions. Previous Interview-based research showed clinical…

Objective: This study aimed to objectively assess signs of hyperactivity in adults suspected of having ADHD, addressing potential sex bias in diagnosis. Methods: About 13,179 (49% female) adults with an average age of 33 years with ADHD and 1,910 (41% female) adults with an average age of 36 years without ADHD were included. Motor activity was…

Objective: There is growing evidence of involvement of inflammatory mechanisms in ADHD. Previous studies found significantly higher rates of ADHD among children with FMF. The present study examined the rate of exposure to FMF in children with a later (within a 5-year period) diagnosis of ADHD compared to non-ADHD children. Methods: A…

Objective: This study aimed to compare the approval of medicines for attention deficit/hyperactivity disorder (ADHD) for pediatric patients across five countries. Method: A document analysis was completed, using the drug labeling for ADHD medicines from five countries; United Kingdom, Australia, New Zealand, Canada and United States (US).…

Objective: Around 70% of adolescents with ADHD experience sleep and/or homework problems. Both impairments have been previously associated with neuropsychological deficits but have not been simultaneously examined in adolescents with ADHD and clinical sleep problems. Therefore, this study investigated how sleep problems are associated with…

Although sometimes perceived as a well-known condition, there are numerous aspects of Attention Deficit Hyperactivity Disorder (ADHD) which we do not fully understand. Given the preponderance of previous ADHD research with males, the need for understanding females' experiences of living with the condition is pressing. This article presents…

Objective: Neurocognitive impairments are associated with child and adult ADHD in clinical settings. However, it is unknown whether adult ADHD symptoms in the general population are associated with the same pattern of cognitive impairment. We examined this using a prospective, population-based cohort spanning birth to age 25 years. Methods: We…

This systematic literature review was conducted to examine the most studied neurodevelopmental disorders reported in the Kingdom of Saudi Arabia and explore public knowledge, attitudes, and behaviors. Electronic literature databases such as PubMed, Embase, Web of Science, Scopus, CINAHL, and Google Scholar from May 2010 to May 2022. The literature…

Objective: The purpose of this rapid review is to appraise the current evidence-base to inform the development of a new assessment and diagnostic pathway for ADHD presentations in a public health paediatric department in Brisbane. We posited that the standardised WISC-V administration in all ADHD presentations regardless of cognitive indication…

Objective: To examine the association between threatened miscarriage, and neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in offspring by age 14 years. Methods: We used data from the Millennium Cohort Study, a nationally representative longitudinal study of children born in…

Exposure to heavy metals has been associated with affecting children's neurodevelopment, particularly increasing the risk of developing attention-deficit hyperactivity disorder (ADHD). The current exploratory study aims to investigate potential associations between presence of 15 different heavy metals in urine and ADHD. A total of 190 urine…