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Ryan J. Martin; Suzannah Iadarola; Rose Iovannone; Brenna Cavanaugh; Krystal Fontechia; Lynne Levato; Cynthia M. Anderson – Journal of Developmental and Physical Disabilities, 2024
Implementation of evidence-based practices for autistic students must be informed by robust research literature. Randomized-controlled trials (RCTs) are often considered a "gold standard" methodology for determining the effectiveness of interventions. However, the complex nature of schools presents challenges for implementing successful…
Descriptors: Autism Spectrum Disorders, Students with Disabilities, Intervention, Randomized Controlled Trials
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Cristina Vargas; Daniela Paoletti; Simona De Stasio; Carmen Berenguer – Autism: The International Journal of Research and Practice, 2025
Sleep disturbances are one of the most common comorbidities in autistic children and adolescence. Considering the impact of sleep disorders on development and daily functioning, it is important to know which treatments are considered effective in literature. This systematic review and meta-analysis study specifically aimed to investigate the…
Descriptors: Sleep, Children, Adolescents, Autism Spectrum Disorders
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Jianjun Ou; Robert C. Smith; Russell H. Tobe; Jingjing Lin; Jen Arriaza; Jed W. Fahey; Ruiting Liu; Ying Zeng; Yanan Liu; Lian Huang; Yidong Shen; Yamin Li; Daomeng Cheng; Brian Cornblatt; John M. Davis; Jingping Zhao; Renrong Wu; Hua Jin – Journal of Autism and Developmental Disorders, 2024
Sulforaphane has been reported to possibly improve core symptoms associated with autism spectrum disorders from mostly small size studies. Here we present results of a larger randomized clinical trial (N = 108) in China. There were no significant changes in caregiver rated scales between sulforaphane and placebo groups. However, clinician rated…
Descriptors: Drug Therapy, Outcomes of Treatment, Autism Spectrum Disorders, Randomized Controlled Trials
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Lucy Beasant; Alba Realpe; Sarah Douglas; Lorcan Kenny; Dheeraj Rai; Nicola Mills – Autism: The International Journal of Research and Practice, 2024
The purpose of this study is to explore the views of autistic adults on randomised controlled trials, specifically on processes such as randomisation and blinding, to understand the barriers and facilitators for recruiting autistic people to randomised controlled trials involving medications. We conducted one-to-one interviews with 49 autistic…
Descriptors: Autism Spectrum Disorders, Adults, Attitudes, Randomized Controlled Trials
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Amanda Timmerman; Vasiliki Totsika; Valerie Lye; Laura Crane; Audrey Linden; Elizabeth Pellicano – Autism: The International Journal of Research and Practice, 2025
Autistic people are more likely to have co-occurring mental health conditions compared to the general population, and mental health interventions have been identified as a top research priority by autistic people and the wider autism community. Autistic adults have also communicated that quality of life is the outcome that matters most to them in…
Descriptors: Adults, Autism Spectrum Disorders, Quality of Life, Randomized Controlled Trials
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Katherine Pye; Hannah Jackson; Teresa Iacono; Alan Shiell – Journal of Autism and Developmental Disorders, 2024
Many autistic children access some form of early intervention, but little is known about the value for money of different programs. We completed a scoping review of full economic evaluations of early interventions for autistic children and/or their families. We identified nine studies and reviewed their methods and quality. Most studies involved…
Descriptors: Economics, Early Intervention, Autism Spectrum Disorders, Children