Conventional random-effects models in meta-analysis rely on large sample approximations instead of exact small sample results. While random-effects methods produce efficient estimates and confidence intervals for the summary effect have correct coverage when the number of studies is sufficiently large, we demonstrate that conventional methods…

Checking for possible inconsistency between direct and indirect evidence is an important task in network meta-analysis. Recently, an evidence-splitting (ES) model has been proposed, that allows separating direct and indirect evidence in a network and hence assessing inconsistency. A salient feature of this model is that the variance for…

Meta-analyses have become the gold standard for synthesizing evidence from multiple clinical trials, and they are especially useful when outcomes are rare or adverse since individual trials often lack sufficient power to detect a treatment effect. However, when zero events are observed in one or both treatment arms in a trial, commonly used…

The "LFK" index has been promoted as an improved method to detect bias in meta-analysis. Putatively, its performance does not depend on the number of studies in the meta-analysis. We conducted a simulation study, comparing the "LFK" index test to three standard tests for funnel plot asymmetry in settings with smaller or larger…

Recently, there has been a growing interest in the potential of virtual reality-based teacher training (VRBTT). Despite this surge, the impact of VRBTT on teacher training outcomes remains unclear and cannot be generalized from generic VR-based training approaches. This study aimed to evaluate the overall effects of VRBTT and explore potentially…

Background: Traditionally, meta-analysis of time-to-event outcomes reports a single pooled hazard ratio assuming proportional hazards (PH). For health technology assessment evaluations, hazard ratios are frequently extrapolated across a lifetime horizon. However, when treatment effects vary over time, an assumption of PH is not always valid. The…

Teachers are increasingly using augmented reality (AR) to develop students' higher-order thinking (HOT). As past studies showed mixed results, our "random effects meta-analysis" of 21 effect sizes from 17 studies of 1256 participants determined the overall effect of AR on HOT and accounted for differences across studies via moderator…

This study builds on the simulation framework of a recent paper by Stanley and Doucouliagos ("Research Synthesis Methods" 2023;14;515--519). S&D use simulations to make the argument that meta-analyses using partial correlation coefficients (PCCs) should employ a "suboptimal" estimator of the PCC standard error when…

Anatomy is the cornerstone of medical education. Virtual reality (VR) and augmented reality (AR) technologies are becoming increasingly popular in the development of anatomy education. Various studies have evaluated VR and AR in anatomy education. This meta-analysis aims to evaluate the effectiveness of VR and AR in anatomical education. The…

Drug repurposing refers to the process of discovering new therapeutic uses for existing medicines. Compared to traditional drug discovery, drug repurposing is attractive for its speed, cost, and reduced risk of failure. However, existing approaches for drug repurposing involve complex, computationally-intensive analytical methods that are not…

With technological advancements, the Metaverse is being used to enhance learning effects and learning experience to ensure quality education. However, current empirical studies have produced varying results. Therefore, a meta-analysis was executed, leveraging the capabilities of Version 3 of the Comprehensive Meta-Analysis software to effectively…

Interventions utilizing human-computer interaction (HCI) in autism rehabilitation have gained popularity, yet their efficacy has not been fully elucidated. This meta-analysis assessed 30 international studies from the past decade that employed HCIs for autism intervention. The findings revealed a moderate positive effect (g = 0.484) on improving…

This study aims to identify emerging trends in immersive learning research in teacher education in order to provide researchers with insights into research themes and issues for further exploration. Specifically, the researchers scrutinised the research methods, research outcomes, and technologies employed in immersive learning research in teacher…

Virtual Reality (VR) is gradually integrating into classroom teaching, emerging as a new trend in educational development in the era of artificial intelligence. Desktop virtual reality stands out due to its lower cost and greater convenience. To elucidate the effectiveness of desktop virtual reality in learning, this paper employs a meta-analysis…

This article presents a systematic review of the literature with the aim of providing an updated framework for the scientific production developed in the field of digital competence and inclusive education in Higher Education, as indexed in the Web of Science (WoS) and SCOPUS databases. Twenty-one scientific articles published between 2016-2023…