The use of Augmented Reality (AR) in education combined with local potency such as Naturindo Herbal Garden located at Sendangsari Village, Pengasih District, Yogyakarta, Indonesia as a center for the herbal medicine industry and learning resource for human digestive was identified as an important strategy for developing student learning outcomes. The purpose of this research was to integrate Naturindo Herbal Garden integrated AR booklet to encourage student's curiosity and learning interest about human digestion for grade eleventh. The AR-digestive booklet was developed by author in previous research then used in this research as learning media. This research was a quasi experiment, determination of research sample used simple random sampling to determine the control and experimental classes with 74 students, 3 biology teachers by giving questionnaires to collect students' interests, curiosity and teacher's response. The learning material in the booklet was conceptually correct, equipped with clear and engaging AR animations to support the learning process. The results showed that the local potential-based digestive system AR-booklet was effective for encouraging student's interest (87.5) and curiosity (91.6) with the results of in the high category and t-test value was below 0.5. Teachers stated the use of AR booklet had achieved remarkable results and was very effective. This study recommended the implementation of local potential-integrated AR booklet to facilitate student's curiosity and learning interest as an innovation in the biology learning process.