Integrating scientific disciplines through a transdisciplinary approach is a pivotal component of contemporary learning paradigms, fostering educational experiences that transcend monodisciplinary boundaries and embrace the integration of diverse fields. Addressing this imperative, we collaborated with educators in Indonesia to devise a learning framework that interweaves mathematics, biology, and cultural dimensions by utilizing the context of Tempeh production--a traditional fermented food in Indonesia. This article delineates the intricacies of our pedagogical design, encompassing eight key stages: briefing, contextualization, exploration, action 1 to action 4, and reflection. Furthermore, we present a comprehensive analysis of students' reflective writing, employing thematic analysis across six stages, namely description, feelings, evaluation, analysis, conclusion, and action plan. This initiative seeks to forge connections between scientific disciplines and to furnish students with theoretical knowledge and tangible and pragmatic experiences.