This study employed an alternating treatments design to compare the effects of two types of practice conditions on the subtraction fact fluency in a fifth-grade classroom. Eight, fifth-grade students participated in the study over a 5-week intervention period practicing addition and subtraction facts in a "fact families" condition (A + S) and only subtraction facts in the second condition (S only) delivered using a math app on an iPad®. Results showed seven out of eight students improved their overall subtraction fact fluency and surpassed expected growth rates. Performance was greater for the majority of students when facts were presented in the S only condition in comparison to facts presented in A + S condition. Despite making substantial gains, only four out of eight students were able to move from frustration level to instructional levels with the intervention. The discussion focuses on the procedural and conceptual knowledge of math instruction and the benefits and implications of using the iPad® to supplement math instruction.