In 2002, the Swedish National Food Agency and researchers from Stockholm University made an announcement regarding the presence of acrylamide in carbohydrate-rich foods that are exposed to high temperatures, with cereals, potatoes, and coffee possibly being the most significant sources of ingestion. Although limited data are available on assessing…

DockIT is an interactive molecular docking tool suitable for teaching students about concepts related to drug-receptor interaction. Its most unique feature is the ability to model both local and global conformational change in the receptor based on information derived from the trajectory of a molecular dynamics (MD) simulation. The workshop…

The application of chemistry concepts in biological settings plays an important role in the interdisciplinary field of drug discovery and development. This is true for molecular docking, where an understanding of intermolecular forces and noncovalent interactions is useful for rational drug design and development. Here we report the design and use…

In recent years, single-subject experimental courses have not been able to meet the demands of the comprehensive development of life sciences. This study is based on two fundamental disciplines, molecular biology and metabolomics, with the analysis and intervention of tumor-related genes as the starting point. A comprehensive experimental course…

Case-based learning (CBL) is a learner-centric educational approach that fosters independent learning and exploration through case analysis, guided by teachers' heuristic instruction. The study aimed to evaluate the efficacy of CBL versus traditional teaching methods in advanced breast cancer education for residents. In this randomized controlled…

We describe an innovative, semester-long course in biology and communication skills for master's degree students in biostatistics. The primary goal of the course is to make the connection between biological science and statistics more explicit. The secondary goals are to teach oral and written communication skills in an appropriate context for…

One of the important mechanisms in cancer cell metastasis is the cellular function of a specific cell type called myofibroblast cells. Myofibroblast cells are unique cell types that play an important role in the cancer cell microenvironment. As a step toward integrating the latest peer-reviewed cancer research findings into a general biology…

Course-based undergraduate research experiences (CUREs) allow students to apply the scientific method to novel questions, which can serve as a gateway for mentored research. Here, we present a model for using cross-disciplinary CUREs to vertically integrate courses from different disciplines. This approach creates opportunities for students to (1)…

Background: Although cutting-edge chemistry research can be an interesting and motivating context for students in pre-university education, few characteristics of supportive and effective learning materials based on such contexts are available. Purpose: In this study we investigated the design, implementation, and evaluation of context-based…

Undergraduate laboratory exercises addressing aspects of cancer biology such as increased cell proliferation, gain-of-function signaling mutations and tumour formation often rely on tissue culture or even small mammal models. Many departments have limited or no access to these tools, and even well-equipped departments face logistical problems when…

Next Generation Sequencing (NGS) has become an important tool in the biological sciences and has a growing number of applications across medical fields. Currently, few undergraduate programs provide training in the design and implementation of NGS applications. Here, we describe an inquiry-based laboratory exercise for a college-level molecular…

Laboratory courses should cultivate enthusiasm for research and an appreciation for real-world scientific challenges to retain undergraduate students and encourage them to pursue STEM-related careers. Course-based undergraduate research experiences (CURE) have emerged as an inclusive pedagogical model that facilitates laboratory skill development,…

Histological assessment of tissues is a critical component of diagnosing diseases and determining disease severity or stage. In order to fully appreciate tissue pathology, an understanding of healthy tissue layers is required. Students traditionally learn this information by memorizing different layers within healthy tissue. This is often a…

Biomimicry is a useful method to develop students' skills, such as design and systems thinking, particularly when complemented with inquiry-based learning. The research seeks to uncover how students engage in the biomimicry process and what types of designs they produce to reveal insights that could assist educators in teaching biomimicry. A study…

The impact of evolutionary processes in understanding human health and disease is an important idea for future health professionals to understand. These students, however, typically receive little to no formal instruction in the role of evolution in not only understanding human health, but its impact on how to treat human diseases. To address this…