The purpose of the present study is to investigate students' understanding of Religious instruction and more specifically the understanding of the Parable of the Prodigal Son, using a didactic approach with the aid of Information and Communication Technologies (ICT). The sample was comprised of two identical classes of 20 pupils each, aged 6 to 7, attending the first grade of primary school in Heraklion, Crete. Quantitative planning and more specifically experimental research were used to conduct this research. The sample was divided into two groups, an experimental one and a control one. The experimental group was taught through an intervention using ICTs as an auxiliary of teaching. The control group was taught according to the traditional instruction. The results showed significant improvement in the understanding of the Parable of the Prodigal Son in the experimental group in comparison to the control group.