This paper reports the contribution of human resource management practices to the effectiveness of Senior High School Management. A quantitative research approach and a descriptive research design were adopted. A sample of 120 respondents were selected for the study using census survey and simple random sampling. A questionnaire was used to gather data from the respondents. The data were analysed using descriptive and inferential statistics. It was found that the factors that highly affect the smooth implementation of human resource management practices were adequate infrastructure, finance, effective leadership, quality staff, increased in students' population, effective training and collaboration. There was a positive and significant relationship between the effectiveness of school management and the implementation of human resource management practices. Therefore, there is the need for management to prioritise the use of resources and provide guidance for the staff in the respective schools.