This study used data from the Beginning Postsecondary Students Longitudinal Study to examine the demographic and in-college characteristics of students with disabilities at 2-year institutions, identify the types of educational services available to them, and determine how students' disability conditions and their selected demographic and in-college characteristics related to their persistence. Nearly 25% of the students with disabilities in the sample did not persist beyond their first year, and almost 51% left without return by the end of their third year. The results from chi-square tests revealed that nonpersistence was associated with depression, physical or orthopedic conditions, and other conditions not specified in the survey. Delayed enrollment decreased the likelihood of both first-to-second and 3-year persistence. Conversely, full-time enrollment, high grade point averages (GPAs), high degree aspirations, and meetings with academic advisors were positively related to persistence. Recommendations for faculty members, administrators, and disability services staff members at 2-year institutions are provided. (Contains 4 tables.)