This paper's main objective is to show relations between interest in media, perceived social support and adolescents' personal well-being. For this purpose, 1,589 Brazilian adolescents answered a questionnaire containing Cummins' Personal Well-Being, Vaux's Social Support Appraisals and Casas' interest in media scales. The media in study are: The Internet, computer games, video games, computer, cell phone and television. For the data analysis this research used Structural Equation Modeling, a statistical methodology based on the confirmation of hypotheses previously established by theoretical frameworks on data. A final model of relations between media, support and well-being was obtained with a fit considered satisfactory by the literature. Implications of media on adolescents' well-being based on this model are considered.