International students comprise over 50% of the graduate student population in the life sciences in the US, over 70% of whom are Asian. Research that aims to understand international students' experiences has often treated Asian students as a monolith, discounting significant cultural and historical differences between regions in Asia that may affect students' motivations for pursuing graduate degrees, their experiences in graduate school, and their identities as scientists in training. To begin to understand the experiences of SAI students as they transition to PhD programs in the sciences, we conducted an exploratory study in which we interviewed 10 SAI students and 12 US native students during the first six months of their doctoral programs. We performed a content analysis of the interview data with the aim of identifying factors that shaped students' doctoral transitions. We then selected factors that were distinctive to SAI students. Finally, we carried out an interpretative phenomenological analysis to understand and describe the following factors that SAI students experienced as influencing their doctoral transitions: prior exposure to research; opportunities for networking; challenges with and affordances for acculturation; attitudes toward and understanding of mental health issues; financial affordances and constraints of pursuing a PhD, and barriers to communication. The results of this work have the potential to be useful to graduate programs seeking to ease SAI students' transition to doctoral programs.