The study investigated the perception of undergraduate students on the use of a Learning Management System (LMS) in the teaching-learning process. The study employed a descriptive survey design. The data for the study were collected using online questionnaires. The study sample comprised 551 undergraduate students from five colleges in Osun State University. The study found a significant difference in undergraduate students' perception of the use of LMS in instructional delivery based on gender, class levels and area of speciliasation. The results showed that the LMS is helpful in reflecting on students' knowledge gaps when preparing for classes. It also revealed that the cost for accessing the LMS, power failures and poor Internet services are major challenges in using the LMS platform. Hence, the study recommends students and lecturers should be encouraged to improve on their computer literacy skills to enhance their usage of the LMS and the use of the LMS should be improved upon and made functional by universities to facilitate blended learning.