One question frequently arises in the work of the Regional Comprehensive Centers: "What are states, districts, and schools doing about RTI?" This document addresses that question, with particular focus on instruction and the implementation of effective practices. It uses a frequently asked questions (FAQs) format, with answers based on the collective experience, to date, of five (three elementary and two middle) public U.S. schools that are implementing elements of Response to Intervention (RTI), including evidence-based instruction, progress monitoring, structures for regulating the intensity of intervention, and professional development. Information was gathered by phone interviews and site visits during Spring 2007 with the five participating sites. Questions were submitted by Regional Comprehensive Centers and answers developed by the Center on Instruction (COI) in collaboration with key individuals from the visited sites. Before addressing the questions, this document provides a broad overview of Response to Intervention. The primary audiences for the material presented here are the Regional Comprehensive Centers and their client state departments of education. The information may also be of interest to persons working in schools and school districts that are considering RTI or working on its implementation. Appended are: (1) Response to Intervention; (2) Selecting RTI Implementation Sites; (3) RTI Glossary; (4) Site Demographics; and (5) Brief Site Descriptions. (Contains 2 tables and 7 footnotes.)