This paper details methods that were adopted during the transition to an online learning environment for students enrolled in Human Anatomy & Physiology and Microbiology courses at a community college designated as a Minority Serving Institution (MSI) in light of shelter-in-place orders established to mitigate the spread of COVID-19. Traditionally carried out in a physical setting, strategies for teaching inquiry-based activities using virtual software will be described. The use of home laboratory science kits for the purposes of engaging students, aligning with Texas Higher Education Coordinating Board (THECB), and maintaining a hands-on approach will also be described. Challenges of transitioning to online instruction and how they were addressed will be further discussed.