In this study, it was aimed to investigate the change blindness that may occur in multimedia learning environments used cueing and signaling effects. For this purpose, a multimedia animation which had some changes about computer parts was designed. Twenty-one undergraduate students participated in the experiment voluntarily. Eye and mouse movements were recorded and analysed with eye-tracking method, and participants were asked to say when they noticed the changes; their voices were simultaneously recorded. The results show that the participants were more focused on the objects being signaled, and less detected the changes in other areas. It is seen that the percentage of detecting the change occurring on the most focused object is low, except for the object using the signaling and visual cueing. The change in the object that was used the signaling and the visual cueing is the most detected change.